SCHEMBL6373385

SCHEMBL6373385

NCCC[C@H](NNO)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.47
CPB2 Q96IY4 5/20 0.44
GSR P00390 1/20 0.42
RNPEP Q9H4A4 1/20 0.41
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
GGT1 P19440 1/20 0.38
SLC6A5 Q9Y345 1/20 0.37
GNPAT O15228 1/20 0.36
GABRR1 P24046 3/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
GABRR3 A8MPY1 1/20 0.34
GABRP O00591 1/20 0.34
GABRD O14764 1/20 0.34
HDAC3 O15379 1/20 0.34
GABBR2 O75899 1/20 0.34
LMNA P02545 1/20 0.34
CYP1A2 P05177 1/20 0.34
THRB P10828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29396372 0.89 FOLH1 (0.52) FOLH1CPB2GSRRNPEPMMP2
SCHEMBL29669470 0.85 FOLH1 (0.58) FOLH1CPB2GSRRNPEPMMP2
SCHEMBL1705338 0.83 FOLH1 (0.47) FOLH1CPB2GSRRNPEPMMP2
SCHEMBL1705339 0.83 FOLH1 (0.47) FOLH1CPB2GSRRNPEPMMP2
SCHEMBL472934 0.83 FOLH1 (0.50) FOLH1CPB2GSRRNPEPMMP2
SCHEMBL29390540 0.83 FOLH1 (0.59) FOLH1CPB2GSRRNPEPMMP2
SCHEMBL472935 0.83 FOLH1 (0.50) FOLH1CPB2GSRRNPEPMMP2
SCHEMBL29894486 0.83 FOLH1 (0.59) FOLH1CPB2GSRRNPEPMMP2
SCHEMBL472937 0.83 FOLH1 (0.50) FOLH1CPB2GSRRNPEPMMP2
SCHEMBL5970038 0.81 FOLH1 (0.42) FOLH1CPB2GSRRNPEPMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050192232-A1 Novel acyl-dipeptide-like compounds bearing an accessory functional side chain spacer, a method for preparing the same and pharmaceutical compositions containing such products OM PHARMA (CH) 2005-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050192232-A1 Novel acyl-dipeptide-like compounds bearing an accessory functional side chain spacer, a method for preparing the same and pharmaceutical compositions containing such products PIGS, AADAT, CD74 FOLH1 460/4885CPB2 695/4885GSR 3510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.