SCHEMBL29397121

SCHEMBL29397121

COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccsc2C(=O)O)n1

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EDNRA P25101 3/20 0.43
MEN1 O00255 1/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
KMT2A Q03164 1/20 0.40
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
FABP4 P15090 3/20 0.39
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL65522 1.00 EDNRA (0.43) EDNRAMEN1CYP3A4TSHRKMT2A
SCHEMBL9715135 1.00 EDNRA (0.43) EDNRAMEN1CYP3A4TSHRKMT2A
Ammonia Solution, Strong SCHEMBL9536160 0.99 EDNRA (0.42) EDNRAMEN1CYP3A4TSHRKMT2A
Thifensulfuron-Methyl SCHEMBL2442597 0.96 EDNRA (0.43) EDNRAMEN1CYP3A4TSHRKMT2A
SCHEMBL9669572 0.93 EDNRA (0.43) EDNRAMEN1CYP3A4TSHRKMT2A
Thifensulfuron-Methyl SCHEMBL29463414 0.92 EDNRA (0.46) EDNRAMEN1TSHRKMT2ALMNA
Thifensulfuron-Methyl SCHEMBL20723624 0.92 EDNRA (0.46) EDNRAMEN1TSHRKMT2ALMNA
Thifensulfuron-Methyl SCHEMBL9139398 0.92 EDNRA (0.46) EDNRAMEN1TSHRKMT2ALMNA
SCHEMBL15905746 0.92 GAA (0.39) EDNRAGAAMAPTKDM4ENPC1
Thifensulfuron-Methyl SCHEMBL53606 0.92 EDNRA (0.46) EDNRAMEN1TSHRKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4519346-A1 SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS Dow Silicones Corporation (US) 2025-03-12 EP disclosed
CN-113195507-B Multifunctional organosilicon compounds and related methods, compounds, and compositions 美国陶氏有机硅公司 2024-09-10 CN disclosed
WO-2023215360-A1 SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORPORATION (US) 2023-11-09 WO disclosed
EP-3508062-B1 HERBICIDAL WEED CONTROL FROM COMBINATIONS OF FLUROXYPYR AND ALS INHIBITORS CORTEVA AGRISCIENCE LLC (US) 2023-10-25 EP disclosed
CN-110997757-B Isocyanate-functional silicone-polyether copolymers, silicone-polyether-urethane copolymers formed therewith, sealants including the same, and related methods 美国陶氏有机硅公司 2022-03-08 CN disclosed