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Thifensulfuron-Methyl

Thifensulfuron-Methyl

SCHEMBL2442597

COC(=O)c1sccc1S(=O)(=O)NC(=O)Nc1nc(C)nc(OC)n1.COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccsc2C(=O)O)n1

nearest known ligand 0.58

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Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ EDNRA P25101 6/20 0.43
▸ PPARG P37231 1/20 0.39
▸ PPARD Q03181 1/20 0.39
▸ PPARA Q07869 1/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ MAPT P10636 1/20 0.38
▸ POLB P06746 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL9536160 0.97 EDNRA (0.42) EDNRAMEN1KMT2AMAPTCYP3A4
Thifensulfuron-Methyl SCHEMBL53606 0.96 EDNRA (0.46) EDNRAPPARGPPARDPPARAMEN1
Thifensulfuron-Methyl SCHEMBL29463414 0.96 EDNRA (0.46) EDNRAPPARGPPARDPPARAMEN1
Thifensulfuron-Methyl SCHEMBL9139398 0.96 EDNRA (0.46) EDNRAPPARGPPARDPPARAMEN1
Thifensulfuron-Methyl SCHEMBL20723624 0.96 EDNRA (0.46) EDNRAPPARGPPARDPPARAMEN1
SCHEMBL65522 0.96 EDNRA (0.43) EDNRAMEN1KMT2AMAPTCYP3A4
SCHEMBL9715135 0.96 EDNRA (0.43) EDNRAMEN1KMT2AMAPTCYP3A4
SCHEMBL29397121 0.96 EDNRA (0.43) EDNRAMEN1KMT2AMAPTCYP3A4
Thifensulfuron-Methyl SCHEMBL8522249 0.93 PPARG (0.41) EDNRAPPARGPPARDPPARAMEN1
SCHEMBL10754403 0.90 EDNRA (0.47) EDNRAPPARGPPARDPPARAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2547766-A2 HERBICIDE-TOLERANT PLANTS BASF Agrochemical Products, B.V. (NL) 2013-01-23 — — EP disclosed
WO-2011114232-A2 HERBICIDE-TOLERANT PLANTS BASF AGROCHEMICAL PRODUCTS B.V. (NL) 2011-09-22 — — WO disclosed
EP-0574418-B1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1998-11-11 — — EP disclosed
EP-0574418-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS Hoechst Schering AgrEvo GmbH (DE) 1993-12-22 — — EP disclosed
WO-1992013845-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-20 — — WO disclosed