Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 1.00 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993421 | 1.00 | NLRP3 (1.00) | NLRP3DNMT3AHDAC1HDAC6 | |
| SCHEMBL11752364 | 1.00 | NLRP3 (1.00) | NLRP3DNMT3AHDAC1HDAC6 | |
| SCHEMBL30323868 | 0.93 | NLRP3 (0.86) | NLRP3DNMT3A | |
| SCHEMBL29388005 | 0.91 | NLRP3 (0.84) | NLRP3DNMT3A | |
| SCHEMBL11851297 | 0.90 | NLRP3 (0.82) | NLRP3DNMT3A | |
| SCHEMBL3782645 | 0.90 | NLRP3 (0.82) | NLRP3DNMT3AHDAC1HDAC6 | |
| SCHEMBL28973056 | 0.88 | NLRP3 (0.79) | NLRP3DNMT3A | |
| SCHEMBL29516883 | 0.88 | NLRP3 (1.00) | NLRP3DNMT3A | |
| SCHEMBL16261128 | 0.88 | NLRP3 (1.00) | NLRP3DNMT3A | |
| SCHEMBL29623532 | 0.88 | NLRP3 (1.00) | NLRP3DNMT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4518845-A1 | COMPLEXES FOR DELIVERY OF NUCLEIC ACIDS | BioNTech SE (DE) | 2025-03-12 | — | — | EP | claimed |
| WO-2023232747-A1 | COMPLEXES FOR DELIVERY OF NUCLEIC ACIDS | BioNTech SE (DE) | 2023-12-07 | — | — | WO | claimed |
| EP-4518845-A1 | COMPLEXES FOR DELIVERY OF NUCLEIC ACIDS | BioNTech SE (DE) | 2025-03-12 | — | — | EP | disclosed |
| CN-119562807-A | Complexes for delivery of nucleic acids | 生物技术公司 | 2025-03-04 | — | — | CN | disclosed |
| WO-2024261302-A1 | NLRP3 INHIBITORS, PAK1/2 INHIBITORS AND/OR CASPASE 1 INHIBITORS FOR USE IN THE TREATMENT OF RAC2 MONOGENIC DISORDERS | Institut National de la Santé et de la Recherche Médicale (FR) | 2024-12-26 | — | — | WO | disclosed |
| CN-113582889-B | Sulfonylureas and related compounds and uses thereof | 昆士兰大学 | 2024-09-20 | — | — | CN | disclosed |
| WO-2023232747-A1 | COMPLEXES FOR DELIVERY OF NUCLEIC ACIDS | BioNTech SE (DE) | 2023-12-07 | — | — | WO | disclosed |
| CN-115297855-A | Methods of treating NLRP 3-associated diseases | 索芙特海尔公司 | 2022-11-04 | — | — | CN | disclosed |
| WO-2022084300-A1 | METHODS FOR DIAGNOSIS AND MONITORING FORM OF CORONAVIRUS INFECTION | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2022-04-28 | — | — | WO | disclosed |
| EP-3956446-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF NLRP3 INFLAMMASOME MEDIATED IL-1BETA DEPENDENT DISORDERS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2022-02-23 | — | — | EP | disclosed |