SCHEMBL2939735

SCHEMBL2939735

C=C(C)C(=O)CCN1CCCC1=O

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.49
TSHR P16473 3/20 0.46
PIK3CD O00329 1/20 0.43
LMNA P02545 1/20 0.41
MEN1 O00255 1/20 0.40
PKM P14618 1/20 0.40
RAB9A P51151 3/20 0.39
NPC1 O15118 2/20 0.39
BRD4 O60885 1/20 0.38
BRD2 P25440 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18300763 0.90 TSHR (0.47) KMT2ATSHRPIK3CDLMNAMEN1
SCHEMBL24774945 0.90 KMT2A (0.47) KMT2ATSHRPIK3CDMEN1RAB9A
SCHEMBL24015908 0.84 KMT2A (0.49) KMT2ATSHRPIK3CDLMNAMEN1
SCHEMBL13804326 0.82 KMT2A (0.54) KMT2ATSHRPIK3CDLMNAMEN1
SCHEMBL14235642 0.79 TSHR (0.48) KMT2ATSHRPIK3CDLMNAMEN1
Methacrylic Acid SCHEMBL1817345 0.79 KMT2A (0.48) KMT2ATSHRPIK3CDMEN1PKM
SCHEMBL4076721 0.78 KMT2A (0.50) KMT2ATSHRPIK3CDLMNAMEN1
SCHEMBL443220 0.77 TSHR (0.53) KMT2ATSHRPIK3CDLMNAMEN1
SCHEMBL9471187 0.77 TSHR (0.54) KMT2ATSHRPIK3CDLMNA
SCHEMBL163326 0.76 KMT2A (0.46) KMT2ATSHRPIK3CDMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8722600-B2 Polymers with H-bridge forming functionalities for improving anti-wear protection EVONIK ROHMAX ADDITIVES GMBH (DE) 2014-05-13 US disclosed
US-8476387-B2 Catalytic process for preparing (meth)acrylic esters of N-hydroxyalkylated lactams BASF SE (DE) 2013-07-02 US disclosed
CN-101300220-B Catalytic process for preparing (meth) acrylic esters from N-hydroxyalkylated lactams BASF AG 2013-02-20 CN disclosed
CN-101622228-B Catalytic process for preparing (meth) acrylic esters of N-hydroxyalkylated lactams BASF SE 2013-01-09 CN disclosed
US-8349779-B2 Polymers with h-bridge forming functionalities EVONIK ROHMAX ADDITIVES GMBH (DE) 2013-01-08 US disclosed
EP-1945602-B1 HYDROGEN-CATALYSED PROCESS FOR PREPARING (METH)ACRYLATES OF N-HYDROXY­ALKYLATED LACTAMS BASF SE (DE) 2012-08-01 EP disclosed
US-7750100-B2 Catalytic process for preparing (meth)acrylates from N-hydroxyalkylated lactams BASF AKTIENGESELLSCHAFT (DE) 2010-07-06 US disclosed
US-20100010236-A1 CATALYTIC PROCESS FOR PREPARING (METH)ACRYLIC ESTERS OF N-HYDROXYALKYLATED LACTAMS BASF SE (DE) 2010-01-14 US disclosed
CN-101622228-A Catalytic process for preparing (meth) acrylic esters of N-hydroxyalkylated lactams BASF SE 2010-01-06 CN disclosed
EP-2121595-A1 METHOD FOR PRODUCING (METH)ACRYLIC ESTERS OF N-HYDROXYALKYLATED LACTAMS BASF SE (DE) 2009-11-25 EP disclosed
CN-101300220-A Catalytic process for preparing (meth) acrylic esters from N-hydroxyalkylated lactams BASF AG (DE) 2008-11-05 CN disclosed
WO-2008098885-A1 METHOD FOR PRODUCING (METH)ACRYLIC ESTERS OF N-HYDROXYALKYLATED LACTAMS BASF SE (DE) 2008-08-21 WO disclosed
EP-1945602-A1 HYDROGEN-CATALYSED PROCESS FOR PREPARING (METH)ACRYLATES OF N-HYDROXY­ALKYLATED LACTAMS BASF SE (DE) 2008-07-23 EP disclosed
US-20070197409-A1 Polymers with h-bridge forming functionalities for improving anti-wear protection EVONIK DEGUSSA GMBH (DE) 2007-08-23 US disclosed
US-20070184993-A1 Polymers with h-bridge forming functionalities ROHMAX ADDITIVES GMBH (DE) 2007-08-09 US disclosed
US-20070123673-A1 CATALYTIC PROCESS FOR PREPARING (METH)ACRYLATES FROM N-HYDROXYALKYLATED LACTAMS BASF AKTIENGESELLSCHAFT (DE) 2007-05-31 US disclosed
WO-2007051738-A1 HYDROGEN-CATALYSED PROCESS FOR PREPARING (METH)ACRYLATES OF N-HYDROXY­ALKYLATED LACTAMS BASF SE (DE) 2007-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100010236-A1 CATALYTIC PROCESS FOR PREPARING (METH)ACRYLIC ESTERS OF N-HYDROXYALKYLATED LACTAMS COASY, MCCC2, PAM KMT2A 863/4885TSHR 2358/4885PIK3CD 1127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.