Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of L-Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Lactic Acid SCHEMBL28619730 | 1.00 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL975525 | 1.00 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL29397432 | 1.00 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL118974 | 1.00 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL15362198 | 0.96 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL16949958 | 0.96 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL9688194 | 0.96 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL15389705 | 0.96 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL4093708 | 0.96 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL29401074 | 0.96 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12178205-B2 | Systems and methods for storing and preserving implantable devices | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2024-12-31 | — | — | US | claimed |
| WO-2022236273-A1 | SYSTEMS AND METHODS FOR STORING AND PRESERVING IMPLANTABLE DEVICES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2022-11-10 | — | — | WO | claimed |
| EP-2785358-B1 | INSULIN-MIMETICS AS THERAPEUTIC ADJUNCTS FOR BONE REGENERATION | UNIV RUTGERS (US) | 2022-06-01 | — | — | EP | claimed |
| CN-114468225-A | Preparation method of selenium-and zinc-rich whole-grain recombinant rice | 哈尔滨商业大学 | 2022-05-13 | — | — | CN | claimed |
| EP-3413844-B1 | ALLOGRAFT TISSUE EXHIBITING ANTIMICROBIAL ACTIVITY AND METHOD FOR PRODUCING THE SAME | UNIV RUTGERS (US) | 2022-04-06 | — | — | EP | claimed |
| US-20220088271-A1 | METHODS FOR PREPARING TISSUE GRAFTS WITH ANTIMICROBIAL PROPERTIES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2022-03-24 | — | — | US | claimed |
| US-20250059486-A1 | CELL-CONTROLLED PERFUSION IN CONTINUOUS CULTURE | BOEHRINGER INGELHEIM INT (DE) | 2025-02-20 | — | — | US | disclosed |
| US-12178205-B2 | Systems and methods for storing and preserving implantable devices | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2024-12-31 | — | — | US | disclosed |
| US-12173267-B2 | Cell-controlled perfusion in continuous culture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-12-24 | — | — | US | disclosed |
| US-11938248-B2 | Electrospinning with sacrificial template for patterning fibrous constructs | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2024-03-26 | — | — | US | disclosed |
| US-20230242857-A1 | CELL-CONTROLLED PERFUSION IN CONTINUOUS CULTURE | BOEHRINGER INGELHEIM INT (DE) | 2023-08-03 | — | — | US | disclosed |
| EP-4148121-A2 | CELL-CONTROLLED PERFUSION IN CONTINUOUS CULTURE | Boehringer Ingelheim International GmbH (DE) | 2023-03-15 | — | — | EP | disclosed |
| US-11597903-B2 | Cell-controlled perfusion in continuous culture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-03-07 | — | — | US | disclosed |
| WO-2022236273-A1 | SYSTEMS AND METHODS FOR STORING AND PRESERVING IMPLANTABLE DEVICES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2022-11-10 | — | — | WO | disclosed |
| EP-2785358-B1 | INSULIN-MIMETICS AS THERAPEUTIC ADJUNCTS FOR BONE REGENERATION | UNIV RUTGERS (US) | 2022-06-01 | — | — | EP | disclosed |
| EP-3303558-B1 | CELL-CONTROLLED PERFUSION IN CONTINUOUS CULTURE | BOEHRINGER INGELHEIM INT (DE) | 2022-05-25 | — | — | EP | disclosed |
| US-20220133607-A1 | Oral Care Composition | COLGATE-PALMOLIVE COMPANY (US) | 2022-05-05 | — | — | US | disclosed |
| EP-3413844-B1 | ALLOGRAFT TISSUE EXHIBITING ANTIMICROBIAL ACTIVITY AND METHOD FOR PRODUCING THE SAME | UNIV RUTGERS (US) | 2022-04-06 | — | — | EP | disclosed |
| US-20220088271-A1 | METHODS FOR PREPARING TISSUE GRAFTS WITH ANTIMICROBIAL PROPERTIES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2022-03-24 | — | — | US | disclosed |
| US-11253444-B2 | Oral care composition | COLGATE-PALMOLIVE COMPANY (US) | 2022-02-22 | — | — | US | disclosed |