Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of L-Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Lactic Acid SCHEMBL1229932 | 1.00 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL15362198 | 1.00 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL435503 | 1.00 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL118974 | 0.96 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL29397605 | 0.96 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL29397432 | 0.96 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL28619730 | 0.96 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL975525 | 0.96 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL25270068 | 0.93 | — | — | |
| L-Lactic Acid SCHEMBL8462013 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608359-A1 | MOUTHWASH COMPOSITIONS AND METHODS | Colgate-Palmolive Company (US) | 2025-09-03 | — | — | EP | claimed |
| US-20240197600-A1 | Mouthwash Compositions and Methods | COLGATE-PALMOLIVE COMPANY | 2024-06-20 | — | — | US | claimed |
| WO-2024123885-A1 | MOUTHWASH COMPOSITIONS AND METHODS | COLGATE-PALMOLIVE COMPANY (US) | 2024-06-13 | — | — | WO | claimed |
| EP-4608359-A1 | MOUTHWASH COMPOSITIONS AND METHODS | Colgate-Palmolive Company (US) | 2025-09-03 | — | — | EP | disclosed |
| CN-119792104-A | Oral care compositions | 高露洁-棕榄公司 | 2025-04-11 | — | — | CN | disclosed |
| US-20240197600-A1 | Mouthwash Compositions and Methods | COLGATE-PALMOLIVE COMPANY | 2024-06-20 | — | — | US | disclosed |
| WO-2024123885-A1 | MOUTHWASH COMPOSITIONS AND METHODS | COLGATE-PALMOLIVE COMPANY (US) | 2024-06-13 | — | — | WO | disclosed |
| EP-3519060-B1 | ORAL CARE COMPOSITIONS WITH INCREASED WHITENING EFFICACY | COLGATE PALMOLIVE CO (US) | 2022-12-14 | — | — | EP | disclosed |
| US-20220133607-A1 | Oral Care Composition | COLGATE-PALMOLIVE COMPANY (US) | 2022-05-05 | — | — | US | disclosed |
| US-11253444-B2 | Oral care composition | COLGATE-PALMOLIVE COMPANY (US) | 2022-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240197600-A1 | Mouthwash Compositions and Methods | TREH, CD44, GLA | TP53 1297/4885CA1 1811/4885CA4 1501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.