Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 9/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM4B | O94953 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.34 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28721905 | 1.00 | PTGS1 (0.36) | PTGS1PTGS2KDM4CKDM4AKDM4B | |
| SCHEMBL3576735 | 0.82 | KDR (0.40) | ESR2SLC22A12 | |
| SCHEMBL2185158 | 0.79 | PDE4A (0.34) | CA2ESR2CA1SLC22A12 | |
| SCHEMBL8501623 | 0.77 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL4490029 | 0.77 | SLC22A12 (0.47) | CA2ESR2CA1SLC22A12 | |
| SCHEMBL28544908 | 0.77 | ESR2 (0.47) | CA2ESR2CA1SLC22A12 | |
| SCHEMBL19643620 | 0.77 | GAK (0.44) | ESR2 | |
| SCHEMBL2423484 | 0.77 | KCNA3 (0.48) | PTGS1PTGS2 | |
| SCHEMBL4525281 | 0.76 | PDE4A (0.35) | CA2ESR2CA1SLC22A12 | |
| SCHEMBL591544 | 0.75 | IDO1 (0.45) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110204544-B | 2- (morpholin-4-yl) -1, 7-naphthyridine | 拜耳制药股份公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-110256427-B | 2- (morpholin-4-yl) -1, 7-naphthyridine | 拜耳制药股份公司 | 2022-02-22 | — | — | CN | disclosed |