Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19643620 | 0.83 | GAK (0.44) | ESR2KDRMAPK14 | |
| SCHEMBL8501623 | 0.83 | SMN1; SMN2 (0.50) | LMNASMN1; SMN2ALDH1A1CASP1KMT2A | |
| SCHEMBL4490029 | 0.83 | SLC22A12 (0.47) | ESR2LMNASMN1; SMN2SYKSLC22A12 | |
| SCHEMBL3551410 | 0.81 | HTR1A (0.46) | LMNASYKMETRIPK2KDR | |
| SCHEMBL3576735 | 0.80 | KDR (0.40) | ESR2SMN1; SMN2ESR1MAPTSLC22A12 | |
| SCHEMBL14999154 | 0.79 | SRC (0.39) | ESR2SMN1; SMN2SLC22A12 | |
| SCHEMBL371799 | 0.78 | PDGFRB (0.51) | MET | |
| SCHEMBL29397704 | 0.77 | PTGS1 (0.36) | ESR2SLC22A12CA1CA2 | |
| SCHEMBL28721905 | 0.77 | PTGS1 (0.36) | ESR2SLC22A12CA1CA2 | |
| SCHEMBL591544 | 0.76 | IDO1 (0.45) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112500341-B | Synthesis method of 7-hydroxyquinoline-4-carboxylic acid | 苏州康润医药有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-112500341-A | Synthesis method of 7-hydroxyquinoline-4-carboxylic acid | 苏州康润医药有限公司 | 2021-03-16 | — | — | CN | disclosed |