Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 15/20 | 0.70 |
| ▸ | KCNJ5 | P48544 | 15/20 | 0.70 |
| ▸ | KCNJ3 | P48549 | 15/20 | 0.70 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25286218 | 0.90 | KCNJ6 (0.72) | KCNJ6KCNJ5KCNJ3MAPK13MAPK12 | |
| SCHEMBL25793175 | 0.88 | KCNJ6 (0.70) | KCNJ6KCNJ5KCNJ3MAPK13MAPK12 | |
| SCHEMBL1780824 | 0.84 | KCNJ6 (0.65) | KCNJ6KCNJ5KCNJ3MAPK13MAPK12 | |
| SCHEMBL3180026 | 0.82 | KCNJ6 (0.51) | KCNJ6KCNJ5KCNJ3MAPK13MAPK12 | |
| SCHEMBL1012856 | 0.78 | KCNJ6 (0.58) | KCNJ6KCNJ5KCNJ3MAPK13MAPK12 | |
| SCHEMBL19258547 | 0.77 | KCNJ6 (0.63) | KCNJ6KCNJ5KCNJ3MAPK13MAPK12 | |
| SCHEMBL1012446 | 0.77 | KCNJ6 (0.52) | KCNJ6KCNJ5KCNJ3BRAFALDH1A1 | |
| SCHEMBL31391128 | 0.73 | KCNJ6 (0.64) | KCNJ6KCNJ5KCNJ3MAPK13MAPK12 | |
| SCHEMBL13975495 | 0.72 | NTRK1 (0.78) | KCNJ6KCNJ5KCNJ3ALDH1A1HTT | |
| SCHEMBL5164195 | 0.72 | CDK8 (0.80) | MAPK13MAPK12MAPK11MAPK14CDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144410-A | Polyarylurea derivatives and their use in the treatment of muscular diseases | 阿纳格纳斯生物技术股份有限公司 | 2022-03-04 | — | — | CN | disclosed |