SCHEMBL29397989

SCHEMBL29397989

COC(=O)[C@H](CO)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.52
CASP3 P42574 2/20 0.52
MDM4 O15151 2/20 0.52
TP53 P04637 2/20 0.52
EPHX2 P34913 1/20 0.49
MDM2 Q00987 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5839367 1.00 KMT2A (0.52) KMT2ACASP3MDM4TP53EPHX2
SCHEMBL29401385 1.00 KMT2A (0.52) KMT2ACASP3MDM4TP53EPHX2
SCHEMBL1486273 1.00 KMT2A (0.52) KMT2ACASP3MDM4TP53EPHX2
SCHEMBL7391110 1.00 KMT2A (0.52) KMT2ACASP3MDM4TP53EPHX2
SCHEMBL10028351 0.91 KMT2A (0.53) KMT2ACASP3MDM4TP53EPHX2
SCHEMBL13863441 0.91 KMT2A (0.53) KMT2ACASP3MDM4TP53EPHX2
SCHEMBL11949183 0.91 CASP3 (0.47) KMT2ACASP3MDM4TP53EPHX2
SCHEMBL377523 0.90 MDM4 (0.50) KMT2ACASP3MDM4TP53EPHX2
SCHEMBL30564455 0.90 MDM4 (0.50) KMT2ACASP3MDM4TP53EPHX2
SCHEMBL29738269 0.90 MDM4 (0.50) KMT2ACASP3MDM4TP53EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122005503-A Ultrasonic response apoptosis bionic targeting nano-carrier delivery material and preparation method thereof 暨南大学 2026-05-12 CN claimed
CN-119954987-A Apoptosis bionic nano drug delivery carrier and preparation method and application thereof 暨南大学 2025-05-09 CN claimed
CN-114315940-A Preparation method of 2-deoxygalactoside 华东师范大学 2022-04-12 CN claimed
CN-122005503-A Ultrasonic response apoptosis bionic targeting nano-carrier delivery material and preparation method thereof 暨南大学 2026-05-12 CN disclosed
US-20260001914-A1 MACROCYCLIC PEPTIDES TARGETING KRAS MERCK SHARP & DOHME LLC (US) 2026-01-01 US disclosed
EP-4558513-A1 MACROCYCLIC PEPTIDES TARGETING KRAS Merck Sharp & Dohme LLC (US) 2025-05-28 EP disclosed
CN-119954987-A Apoptosis bionic nano drug delivery carrier and preparation method and application thereof 暨南大学 2025-05-09 CN disclosed
CN-119504686-A Human cystathionine gamma-lyase response fluorescent dye, and preparation method and application thereof 大连理工大学宁波研究院 2025-02-25 CN disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
WO-2024020159-A1 MACROCYCLIC PEPTIDES TARGETING KRAS MERCK SHARP & DOHME LLC (US) 2024-01-25 WO disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
CN-114315940-A Preparation method of 2-deoxygalactoside 华东师范大学 2022-04-12 CN disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001914-A1 MACROCYCLIC PEPTIDES TARGETING KRAS KRAS, NRAS, HRAS KMT2A 2905/4885CASP3 2464/4885MDM4 1577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.