Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | NAE1 | Q13564 | 5/20 | 0.32 |
| ▸ | UBA3 | Q8TBC4 | 4/20 | 0.32 |
| ▸ | UBA6 | A0AVT1 | 2/20 | 0.32 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.32 |
| ▸ | ATG7 | O95352 | 1/20 | 0.32 |
| ▸ | UBA7 | P41226 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | GRK5 | P34947 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | NEDD8 | Q15843 | 1/20 | 0.31 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22579634 | 1.00 | NT5E (0.38) | NT5EP2RX7PDE2ANAE1UBA3 | |
| SCHEMBL22569901 | 0.87 | PDE2A (0.35) | NT5EPDE2ABCHE | |
| SCHEMBL24557992 | 0.83 | PDE2A (0.38) | NT5EP2RX7PDE2ANAE1UBA3 | |
| SCHEMBL22569914 | 0.81 | PDE2A (0.37) | NT5EPDE2ABCHE | |
| SCHEMBL24557960 | 0.79 | PDE2A (0.36) | PDE2ABCHE | |
| SCHEMBL22569910 | 0.77 | NT5E (0.35) | NT5EPDE2ABCHE | |
| SCHEMBL24941081 | 0.75 | ERN1 (0.34) | NT5EPDE2ABCHE | |
| SCHEMBL30323271 | 0.75 | BCHE (0.34) | NT5EPDE2ABCHE | |
| SCHEMBL22579740 | 0.72 | PDE2A (0.37) | PDE2ABCHE | |
| SCHEMBL13648927 | 0.71 | PDE2A (0.34) | PDE2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3956341-A1 | CD73 INHIBITORS | Bioardis LLC (US) | 2022-02-23 | — | — | EP | disclosed |