Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | NAE1 | Q13564 | 2/20 | 0.34 |
| ▸ | UBA3 | Q8TBC4 | 2/20 | 0.34 |
| ▸ | UBA6 | A0AVT1 | 1/20 | 0.34 |
| ▸ | ATG7 | O95352 | 1/20 | 0.34 |
| ▸ | UBA7 | P41226 | 1/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22579639 | 0.86 | PDE2A (0.41) | PDE2ANT5EBCHEHTR1ACA1 | |
| SCHEMBL22569903 | 0.86 | PDE2A (0.41) | PDE2ANT5EBCHEHTR1ACA1 | |
| SCHEMBL29398012 | 0.83 | NT5E (0.38) | PDE2ANT5EP2RX7BCHENAE1 | |
| SCHEMBL22579634 | 0.83 | NT5E (0.38) | PDE2ANT5EP2RX7BCHENAE1 | |
| SCHEMBL29398438 | 0.79 | PDE2A (0.46) | PDE2ANT5EBCHEHTR1A | |
| SCHEMBL24557950 | 0.78 | HTR1A (0.37) | PDE2ANT5EBCHEHTR1ACA1 | |
| SCHEMBL24557961 | 0.77 | PDE2A (0.41) | PDE2ANT5EBCHEHTR1ACA1 | |
| SCHEMBL22579637 | 0.77 | UBA6 (0.40) | NAE1UBA3UBA6ATG7UBA7 | |
| SCHEMBL29398454 | 0.77 | UBA6 (0.40) | NAE1UBA3UBA6ATG7UBA7 | |
| SCHEMBL22569907 | 0.75 | PDE2A (0.40) | PDE2ANT5EBCHEHTR1ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220204539-A1 | CD73 INHIBITORS | BIOARDIS LLC | 2022-06-30 | — | — | US | disclosed |
| US-20220204539-A1 | CD73 INHIBITORS | BIOARDIS LLC | 2022-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220204539-A1 | CD73 INHIBITORS | ENTPD5, ENTPD1, ENTPD2 | PDE2A 431/4885NT5E 8/4885P2RX7 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.