Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 1/20 | 0.47 |
| ▸ | CCKBR | P32239 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 4/20 | 0.44 |
| ▸ | FNTB | P49356 | 4/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.44 |
| ▸ | GRPR | P30550 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29649733 | 0.90 | OPRD1 (0.49) | OPRM1OPRD1 | |
| SCHEMBL30974516 | 0.88 | OPRD1 (0.53) | OPRM1OPRD1 | |
| SCHEMBL29378934 | 0.88 | FNTA (0.51) | FNTAFNTBPGGT1BLTA4H | |
| SCHEMBL7996617 | 0.86 | FNTA (0.41) | CCKARCCKBRFNTAFNTBPGGT1B | |
| SCHEMBL7996614 | 0.86 | FNTA (0.41) | CCKARCCKBRFNTAFNTBPGGT1B | |
| SCHEMBL30692725 | 0.86 | OPRD1 (0.52) | OPRM1OPRD1 | |
| SCHEMBL30680249 | 0.85 | FNTA (0.38) | FNTAFNTBPGGT1BGRPROPRM1 | |
| SCHEMBL29565203 | 0.85 | FNTA (0.38) | FNTAFNTBPGGT1BGRPROPRM1 | |
| SCHEMBL3511481 | 0.85 | BACE1 (0.44) | CCKARCCKBRFNTAFNTBPGGT1B | |
| SCHEMBL3511477 | 0.85 | BACE1 (0.44) | CCKARCCKBRFNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812062-B1 | ANTI-ADDL ANTIBODIES AND USES THEREOF | MERCK SHARP & DOHME (US) | 2022-03-09 | — | — | EP | claimed |
| EP-1812062-B1 | ANTI-ADDL ANTIBODIES AND USES THEREOF | MERCK SHARP & DOHME (US) | 2022-03-09 | — | — | EP | disclosed |