Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 6/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22569903 | 0.93 | PDE2A (0.41) | PDE2AADORA1BCHEADORA3HTR1A | |
| SCHEMBL22579639 | 0.93 | PDE2A (0.41) | PDE2AADORA1BCHEADORA3HTR1A | |
| SCHEMBL24557986 | 0.83 | PDE2A (0.59) | PDE2ABCHEHTR1ANT5E | |
| SCHEMBL24557950 | 0.83 | HTR1A (0.37) | PDE2ABCHEHTR1ANT5E | |
| SCHEMBL29397151 | 0.82 | PDE2A (0.45) | PDE2ABCHEHTR1A | |
| SCHEMBL22579737 | 0.82 | PDE2A (0.45) | PDE2ABCHEHTR1A | |
| SCHEMBL22569914 | 0.81 | PDE2A (0.37) | PDE2AADORA1BCHEADORA3NT5E | |
| SCHEMBL22579642 | 0.81 | HTR1A (0.36) | PDE2ABCHEHTR1ANT5E | |
| SCHEMBL28406218 | 0.81 | BCHE (0.38) | PDE2AADORA1BCHEADORA3HTR1A | |
| SCHEMBL22569901 | 0.80 | PDE2A (0.35) | PDE2AADORA1BCHEADORA3NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3956341-A1 | CD73 INHIBITORS | Bioardis LLC (US) | 2022-02-23 | — | — | EP | disclosed |