SCHEMBL29398657

SCHEMBL29398657

COc1c2c3c4c(c(OC)c(=O)c5c(O)cc(OC)c(c6c(OC)cc(O)c(c1=O)c63)c54)C(C(C)=O)=C(C)C2

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.47
THRB P10828 2/20 0.47
KMT2A Q03164 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
RECQL P46063 1/20 0.35
MGAM O43451 7/20 0.35
HTT P42858 1/20 0.34
ALOX5 P09917 1/20 0.32
HIF1A Q16665 1/20 0.32
EPAS1 Q99814 1/20 0.32
CTSV O60911 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
GAA P10253 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13121633 1.00 MEN1 (0.47) MEN1THRBKMT2ATDP1RECQL
SCHEMBL5178392 0.93 MEN1 (0.48) MEN1THRBKMT2ATDP1RECQL
SCHEMBL13937289 0.86 MEN1 (0.39) MEN1THRBKMT2ATDP1
SCHEMBL14600288 0.82 MEN1 (0.49) MEN1THRBKMT2ATDP1RECQL
SCHEMBL14302232 0.82 THRB (0.54) MEN1THRBKMT2ATDP1RECQL
SCHEMBL14600289 0.79 MEN1 (0.44) MEN1THRBKMT2ATDP1RECQL
SCHEMBL22212454 0.75 MEN1 (0.38) MEN1THRBKMT2ATDP1RECQL
SCHEMBL14632287 0.70 MEN1 (0.43) MEN1THRBKMT2ATDP1RECQL
SCHEMBL3673245 0.68 MGAM (0.40) MGAMHTTCTSV
Hypocrellin A SCHEMBL13478188 0.68 MEN1 (0.71) MEN1THRBKMT2ATDP1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3366669-B1 MONOSUBSTITUTED OR POLYSUBSTITUTED AMPHIPHILIC HYPOCRELLIN DERIVATIVE, PREPARATION METHOD THEREFOR, AND USES THEREOF TECHNICAL INST OF PHYSICS AND CHEMISTRY OF THE CHINESE ACADEMY OF SCIENCES (CN) 2025-05-21 EP claimed
EP-4532008-A1 ULTRASOUND ARRAYS FOR ENHANCED TISSUE THERAPY Alpheus Medical, Inc. (US) 2025-04-09 EP claimed
US-12178886-B2 Imaging and treatment of pathophysiologic conditions by Cerenkov radiation WASHINGTON UNIVERSITY (US) 2024-12-31 US claimed
US-20240387851-A1 PERYLENEQUINONES FOR REDOX APPLICATIONS NATIONAL INSTITUTES OF HEALTH 2024-11-21 US claimed
CN-118950085-A Preparation method and application of supported hypocrellin visible light catalyst 华南理工大学珠海现代产业创新研究院 2024-11-15 CN claimed
CN-118930986-A Film for reducing blue light transmission and preparation method thereof 华南理工大学珠海现代产业创新研究院 2024-11-12 CN claimed
CN-118806892-A Full-active nano-drug based on traditional Chinese medicine sound sensitizer and hypoxia activated prodrug, and preparation method and application thereof 河南中医药大学 2024-10-22 CN claimed
CN-118307393-A Method for preparing high-purity hypocrellin 山东国力生物技术研究院 2024-07-09 CN claimed
EP-4385499-A1 A METHOD TO ENABLE NANOPARTICLES STORED WITH A SPECIFIC TYPE OF ASSEMBLY TO MAINTAIN THIS TYPE OF ASSEMBLY UPON RECONSTITUTION Nanobacterie (FR) 2024-06-19 EP claimed
CN-118146546-A Preparation method and application of antibacterial and indicating film 西北农林科技大学 2024-06-07 CN claimed
CN-111643673-B Tumor-targeted nano-drug simultaneously encapsulating photosensitizer and protein and application thereof 福建医科大学孟超肝胆医院(福州市传染病医院) 2022-09-13 CN claimed
US-11415516-B2 Method for reduction of autofluorescence from biological samples LEICA MICROSYSTEMS CMS GMBH (DE) 2022-08-16 US claimed
CN-114886869-A Macrophage-based ultrasonic delivery system and construction method and application thereof 江苏大学 2022-08-12 CN claimed
US-20220202961-A1 IMAGING AND TREATMENT OF PATHOPHYSIOLOGIC CONDITIONS BY CERENKOV RADIATION WASHINGTON UNIVERSITY 2022-06-30 US claimed
CN-114644607-A Hypocrellin derivative and preparation method and application thereof 中国科学院化学研究所 2022-06-21 CN claimed
CN-112279757-B Perylene quinone compound and preparation method and application thereof 中国科学院化学研究所 2022-03-29 CN claimed
CN-114209828-A Hypocrellin composite nano particle and preparation method thereof 同济大学 2022-03-22 CN claimed
CN-114162884-A Method for inhibiting harmful algae by using perylenequinone compound 江南大学 2022-03-11 CN claimed
CN-114028566-A Near-infrared light response photosensitizer compound and preparation method and application thereof 天津工业大学 2022-02-11 CN claimed
WO-2022032283-A2 ULTRASOUND ARRAYS FOR ENHANCED SONODYNAMIC THERAPY FOR TREATING CANCER Alpheus Medical, Inc. (US) 2022-02-10 WO claimed