Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Mosapride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 known ✓ | Q13639 | 2/20 | 0.60 |
| ▸ | DRD3 | P35462 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | HTR1A | P08908 | 1/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 1/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 1/20 | 1.00 |
| ▸ | HTR2C | P28335 | 1/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | HTR2B | P41595 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 1.00 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 1.00 |
| ▸ | DRD4 | P21917 | 12/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mosapride SCHEMBL6228981 | 1.00 | DRD3 (1.00) | DRD3MEN1LMNACYP1A2CYP3A4 | |
| Mosapride SCHEMBL16417 | 1.00 | DRD3 (1.00) | DRD3MEN1LMNACYP1A2CYP3A4 | |
| Mosapride SCHEMBL6227991 | 0.99 | DRD3 (0.98) | DRD3MEN1LMNACYP1A2CYP3A4 | |
| Mosapride SCHEMBL2369236 | 0.99 | DRD3 (0.98) | DRD3MEN1LMNACYP1A2CYP3A4 | |
| Mosapride SCHEMBL6225436 | 0.99 | DRD3 (0.98) | DRD3MEN1LMNACYP1A2CYP3A4 | |
| Mosapride SCHEMBL5150929 | 0.98 | DRD3 (0.97) | DRD3MEN1LMNACYP1A2CYP3A4 | |
| Mosapride SCHEMBL6229365 | 0.95 | DRD3 (0.91) | DRD3MEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL7364946 | 0.94 | KCNH2 (0.88) | DRD3MEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL8004478 | 0.93 | DRD3 (0.86) | DRD3MEN1LMNACYP1A2CYP3A4 | |
| Mosapride SCHEMBL258620 | 0.92 | DRD3 (0.85) | DRD3MEN1LMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2974720-B1 | MOSAPRIDE SUSTAINED-RELEASE PREPARATION FOR PROVIDING PHARMACOLOGICAL CLINICAL EFFECTS WITH ONCE-A-DAY ADMINISTRATION | KOREA UNITED PHARM INC (KR) | 2024-02-21 | — | — | EP | claimed |
| CN-109822573-B | Live program online packaging method based on camera robot | 太仓中科信息技术研究院 | 2022-04-22 | — | — | CN | claimed |
| EP-4578401-A1 | AUTOMATED INFLAMMATORY BOWEL DISEASE DETECTION USING BOWEL SOUNDS MONITORED BY A WEARABLE SYSTEM | Hahn-Schickard-Gesellschaft für angewandte Forschung e. V. (DE) | 2025-07-02 | — | — | EP | disclosed |
| CN-119990173-A | Radio frequency identification tag and manufacturing method thereof | 浙江码尚科技股份有限公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-119745968-A | Traditional Chinese medicine and probiotics composition for improving constipation and preparation method thereof | 郑州市大肠肛门病医院 | 2025-04-04 | — | — | CN | disclosed |
| CN-222629292-U | Remote parking device of security equipment | 厦门金龙联合汽车工业有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-119623503-A | Printed radio frequency identification tag and preparation method thereof | 浙江码尚科技股份有限公司 | 2025-03-14 | — | — | CN | disclosed |
| US-12157768-B2 | Anti-LILRB2 antibodies and methods of use thereof | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2024-12-03 | — | — | US | disclosed |
| EP-3847672-B1 | SYSTEMS AND METHODS FOR ELECTROSTATIC ACCELERATOR DRIVEN NEUTRON GENERATION FOR A LIQUID-PHASE BASED TRANSMUTATION | TAE TECH INC (US) | 2024-10-23 | — | — | EP | disclosed |
| CN-118806735-A | Galla Turcica oral cavity film, and preparation method and application thereof | 新疆奇沐医药研究院（有限公司） | 2024-10-22 | — | — | CN | disclosed |
| CN-118781214-A | Satellite optical load simulation imaging method, system, electronic equipment and storage medium | 中国电子科技集团公司信息科学研究院 | 2024-10-15 | — | — | CN | disclosed |
| CN-114539109-B | Beta-ketone sulfosulfone synthesis method | 成都理工大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-112992389-B | Molten salt fast reactor | 中国科学院上海应用物理研究所 | 2022-11-01 | — | — | CN | disclosed |
| CN-115221714-A | Short-term, medium-term and long-term forecasting method and system for weather and atmospheric environment in near space | 北京师范大学 | 2022-10-21 | — | — | CN | disclosed |
| CN-115209911-A | Recombinant micelles and methods of in vivo Assembly | 莫扎食品公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-111627572-B | Modularized molten salt reactor core and molten salt reactor | 中国科学院上海应用物理研究所 | 2022-09-30 | — | — | CN | disclosed |
| CN-114539109-A | Beta-ketosulfolane synthesis method | 成都理工大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-109822573-B | Live program online packaging method based on camera robot | 太仓中科信息技术研究院 | 2022-04-22 | — | — | CN | disclosed |
| US-11304604-B2 | Reflective mode multi-spectral time-resolved optical imaging methods and apparatuses for tissue classification | SPECTRAL MD, INC. (US) | 2022-04-19 | — | — | US | disclosed |
| US-20220056128-A1 | ANTI-LILRB2 ANTIBODIES AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-02-24 | — | — | US | disclosed |