Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18805591 | 1.00 | ATR (0.45) | ATRL3MBTL1GSK3BDYRK1AMKNK2 | |
| SCHEMBL4664375 | 0.84 | NPC1 (0.53) | MAP4K4CDK1EGFRSRCNPC1 | |
| SCHEMBL12705673 | 0.84 | GAA (0.43) | ATRL3MBTL1MAP4K4FGFR4AAK1 | |
| SCHEMBL17265777 | 0.84 | EGFR (0.42) | ATRGSK3BDYRK1AMKNK2MAP4K4 | |
| SCHEMBL690643 | 0.84 | CDK1 (0.49) | MAP4K4FGFR4CDK1EGFRSRC | |
| SCHEMBL18814953 | 0.84 | L3MBTL1 (0.49) | ATRL3MBTL1GSK3BDYRK1AMKNK2 | |
| SCHEMBL19890987 | 0.84 | L3MBTL1 (0.44) | ATRL3MBTL1GSK3BDYRK1AMKNK2 | |
| SCHEMBL18805592 | 0.84 | L3MBTL1 (0.68) | ATRL3MBTL1GSK3BDYRK1AMKNK2 | |
| SCHEMBL10288086 | 0.83 | GSK3B (0.54) | ATRGSK3BDYRK1AMAP4K4PTGER1 | |
| SCHEMBL691488 | 0.83 | CDK1 (0.48) | MAP4K4FGFR4CDK1EGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025022007-A1 | PESTICIDALLY ACTIVE QUINAZOLINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-01-30 | — | — | WO | disclosed |
| US-20240417405-A1 | Substituted Spiro Derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2024-12-19 | — | — | US | disclosed |
| WO-2024159094-A1 | PYRIMIDINYL (HETERO)AROMATIC AMINOPYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-08-02 | — | — | WO | disclosed |
| US-20240092799-A1 | MNK INHIBITORS | HEPAGENE THERAPEUTICS HK LTD (CN) | 2024-03-21 | — | — | US | disclosed |
| EP-4200296-A1 | MNK INHIBITORS | Hepagene Therapeutics (HK) Limited (HK) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022038563-A1 | MNK INHIBITORS | Hepagene Therapeutics (HK) Limited (CN) | 2022-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240092799-A1 | MNK INHIBITORS | MKNK1, MATK, NEK1 | ATR 429/4885L3MBTL1 1524/4885GSK3B 1232/4885 |
| US-20240417405-A1 | Substituted Spiro Derivatives | BMI1, MLLT1, MLLT3 | ATR 1004/4885L3MBTL1 1712/4885GSK3B 1669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.