SCHEMBL29400671

SCHEMBL29400671

CC(C)(C)OC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OC[C@H](NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 2/20 0.52
TP53 P04637 2/20 0.52
MDM2 Q00987 1/20 0.51
IDO1 P14902 1/20 0.50
TNF P01375 3/20 0.47
CASP3 P42574 1/20 0.46
PPARA Q07869 2/20 0.46
TLR2 O60603 2/20 0.45
PPARG P37231 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL598209 0.92 MDM4 (0.56) MDM4TP53MDM2TNFCASP3
SCHEMBL30802551 0.92 MDM4 (0.56) MDM4TP53MDM2TNFCASP3
SCHEMBL29367497 0.92 MDM4 (0.56) MDM4TP53MDM2TNFCASP3
SCHEMBL29355082 0.92 MDM4 (0.56) MDM4TP53MDM2TNFCASP3
SCHEMBL29624621 0.92 MDM4 (0.56) MDM4TP53MDM2TNFCASP3
SCHEMBL119565 0.92 MDM4 (0.56) MDM4TP53MDM2TNFCASP3
SCHEMBL119575 0.92 MDM4 (0.56) MDM4TP53MDM2TNFCASP3
Fluoride SCHEMBL7155195 0.91 MDM4 (0.55) MDM4TP53MDM2TNFCASP3
SCHEMBL29402289 0.89 MDM4 (0.51) MDM4TP53MDM2IDO1TNF
SCHEMBL30562127 0.88 MDM4 (0.53) MDM4TP53MDM2TNFCASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed