SCHEMBL29401101

SCHEMBL29401101

NC(=O)CC[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 3/20 0.56
TP53 P04637 3/20 0.56
TLR2 O60603 2/20 0.55
MDM2 Q00987 6/20 0.52
KMT2A Q03164 2/20 0.51
CASP3 P42574 2/20 0.51
SLC17A5 Q9NRA2 1/20 0.49
PTPN1 P18031 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL800090 1.00 MDM4 (0.56) MDM4TP53TLR2MDM2KMT2A
SCHEMBL5182292 1.00 MDM4 (0.56) MDM4TP53TLR2MDM2KMT2A
SCHEMBL119475 1.00 MDM4 (0.56) MDM4TP53TLR2MDM2KMT2A
SCHEMBL29352431 1.00 MDM4 (0.56) MDM4TP53TLR2MDM2KMT2A
SCHEMBL29908079 1.00 MDM4 (0.56) MDM4TP53TLR2MDM2KMT2A
SCHEMBL29682425 1.00 MDM4 (0.56) MDM4TP53TLR2MDM2KMT2A
SCHEMBL27435787 0.94 MDM2 (0.56) MDM4TP53TLR2MDM2KMT2A
SCHEMBL29694496 0.93 PTPN1 (0.58) MDM4TP53TLR2MDM2KMT2A
SCHEMBL30929979 0.92 TLR2 (0.49) MDM4TP53TLR2MDM2KMT2A
SCHEMBL30255589 0.92 TLR2 (0.49) MDM4TP53TLR2MDM2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12486304-B2 Peptide ligand targeting carbonic anhydrase IX, peptide construct comprising same, and uses thereof C-BIOMEX CO., LTD. (KR) 2025-12-02 US disclosed
US-12435108-B2 Teixobactin analogue and use thereof SUNSHINE LAKE PHARMA CO., LTD. (CN) 2025-10-07 US disclosed
US-20250270257-A1 PEPTIDE LIGAND TARGETING CARBONIC ANHYDRASE IX, PEPTIDE CONSTRUCT COMPRISING SAME, AND USES THEREOF C-BIOMEX CO., LTD. (KR) 2025-08-28 US disclosed
WO-2025089217-A1 COMPOUND FOR USE AS SUBSTRATE FOR EVALUATING ACTIVITY OF γ-D-GLUTAMYL-L-LYSYL ENDOPEPTIDASE 株式会社ヤクルト本社 2025-05-01 WO disclosed
US-20250129125-A1 MACROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF GENENTECH, INC. (US) 2025-04-24 US disclosed
CN-117120458-B Peptide ligands targeting carbonic anhydrase IX, peptide structures comprising the same, and uses thereof C-比奥麦克斯有限公司 2025-04-04 CN disclosed
CN-119638792-A Polypeptide PT-09014 and application thereof in antitumor drugs 科通诺贝生物医药科技(北京)有限公司 2025-03-18 CN disclosed
CN-119504947-A Polypeptide PT-1323 and application thereof in antitumor drugs 科通诺贝生物医药科技(北京)有限公司 2025-02-25 CN disclosed
CN-119320430-A Polypeptide PT-1509 and application thereof in antitumor drugs 科通诺贝生物医药科技(北京)有限公司 2025-01-17 CN disclosed
US-12187816-B2 Macrocyclic compounds and methods of use thereof GENENTECH, INC. (US) 2025-01-07 US disclosed
CN-112300247-B Teixobactin analogue and application thereof 广东东阳光药业有限公司 2022-12-27 CN disclosed
EP-4091623-A1 CALCIUM-SENSING RECEPTOR AGONIST COMPOUND AND APPLICATION THEREOF Beijing Tuo Jie Biopharmaceutical Co. Ltd. (CN) 2022-11-23 EP disclosed
EP-4063378-A1 BIOLOGICAL PEPTIDE FOR TREATING LUNG DISEASES AND APPLICATION THEREOF Shanghai Institute of Pharmaceutical Industry Co., Ltd. (CN) 2022-09-28 EP disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
US-20220273760-A1 A TEIXOBACTIN ANALOGUE AND USE THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2022-09-01 US disclosed
CN-112920256-B Biological peptide for treating asthma and application thereof 上海医药工业研究院 2022-08-19 CN disclosed
CN-112500457-B Dual-targeting FOXM1/CDK1 anti-tumor polypeptide 长沙新生康源生物医药有限公司 2022-06-17 CN disclosed
EP-4004015-A1 A TEIXOBACTIN ANALOGUE AND USE THEREOF Sunshine Lake Pharma Co., Ltd. (CN) 2022-06-01 EP disclosed
US-20220106361-A1 MACROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF GENENTECH, INC. (US) 2022-04-07 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220106361-A1 MACROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF PAICS, CYCS, LSS MDM4 1699/4885TP53 732/4885TLR2 4868/4885
US-20220273760-A1 A TEIXOBACTIN ANALOGUE AND USE THEREOF TALDO1, NAMPT, TES MDM4 3126/4885TP53 1519/4885TLR2 469/4885
US-20250270257-A1 PEPTIDE LIGAND TARGETING CARBONIC ANHYDRASE IX, PEPTIDE CONSTRUCT COMPRISING SAME, AND USES THEREOF CA9, CA4, CA12 MDM4 3083/4885TP53 1936/4885TLR2 3372/4885
US-12187816-B2 Macrocyclic compounds and methods of use thereof PAICS, CYCS, LSS MDM4 1699/4885TP53 732/4885TLR2 4868/4885
US-20250129125-A1 MACROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF PAICS, CYCS, LSS MDM4 1699/4885TP53 732/4885TLR2 4868/4885
US-12486304-B2 Peptide ligand targeting carbonic anhydrase IX, peptide construct comprising same, and uses thereof CA9, CA4, CA12 MDM4 3083/4885TP53 1936/4885TLR2 3372/4885
US-12435108-B2 Teixobactin analogue and use thereof TALDO1, NAMPT, TES MDM4 3019/4885TP53 1531/4885TLR2 419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.