SCHEMBL29401239

SCHEMBL29401239

N=C(N)NCCC[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.53
MDM2 Q00987 6/20 0.52
MDM4 O15151 1/20 0.51
TP53 P04637 1/20 0.51
TLR2 O60603 2/20 0.51
CASP3 P42574 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18237098 1.00 KMT2A (0.53) KMT2AMDM2MDM4TP53TLR2
SCHEMBL29514568 1.00 KMT2A (0.53) KMT2AMDM2MDM4TP53TLR2
SCHEMBL26093325 1.00 KMT2A (0.53) KMT2AMDM2MDM4TP53TLR2
SCHEMBL29875729 1.00 KMT2A (0.53) KMT2AMDM2MDM4TP53TLR2
SCHEMBL15521165 1.00 KMT2A (0.53) KMT2AMDM2MDM4TP53TLR2
SCHEMBL120403 1.00 KMT2A (0.53) KMT2AMDM2MDM4TP53TLR2
Hydrochloric Acid SCHEMBL9661481 0.99 KMT2A (0.52) KMT2AMDM2MDM4TP53TLR2
Hydrochloric Acid SCHEMBL29365362 0.99 KMT2A (0.52) KMT2AMDM2MDM4TP53TLR2
Hydrochloric Acid SCHEMBL29400592 0.99 KMT2A (0.52) KMT2AMDM2MDM4TP53TLR2
SCHEMBL29432853 0.97 KMT2A (0.54) KMT2AMDM2MDM4TP53TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118620027-A Preparation method of icatibant 武汉武药科技有限公司 2024-09-10 CN claimed
CN-116947966-B Method for preparing itracin intermediate and itracin 哈药集团生物工程有限公司 2023-12-26 CN claimed
US-20260124312-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BICYCLETX LIMITED (GB) 2026-05-07 US disclosed
CN-121914210-A Method for preparing ETELCALCETIDE by combining solid and liquid 浙江工业大学 2026-04-24 CN disclosed
US-20250242064-A1 CXCR4-TARGETING COMPOUNDS, AND METHODS OF MAKING AND USING THE SAME ALPHA-9 ONCOLOGY INC. (CA) 2025-07-31 US disclosed
EP-3727461-B1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BICYCLETX LTD (GB) 2025-07-09 EP disclosed
EP-4582436-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BicycleTX Limited (GB) 2025-07-09 EP disclosed
CN-118754946-A Cationic polypeptide with tumor targeted permeation effect and preparation method and application of micelle of cationic polypeptide 上海交通大学医学院附属第九人民医院 2024-10-11 CN disclosed
CN-118620027-A Preparation method of icatibant 武汉武药科技有限公司 2024-09-10 CN disclosed
CN-118620027-A Preparation method of icatibant 武汉武药科技有限公司 2024-09-10 CN disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
EP-4069684-A2 COMPOUNDS AND METHODS FOR AMINE OXIDASE IMAGING ETH Zurich (CH) 2022-10-12 EP disclosed
US-20220289792-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BICYCLETX LIMITED (GB) 2022-09-15 US disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
CN-114773433-B CD25 targeted polypeptide, molecular probe and application 北京肿瘤医院(北京大学肿瘤医院) 2022-09-06 CN disclosed
US-20220218852-A1 NOVEL RADIOLABELLED CXCR4-TARGETING COMPOUNDS FOR DIAGNOSIS AND THERAPY THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2022-07-14 US disclosed
WO-2022149612-A1 METHOD FOR PRODUCING PEPTIDE 日産化学株式会社 2022-07-14 WO disclosed
CN-114364690-A Novel radiolabeled CXCR4 targeting compounds for diagnosis and therapy 省卫生服务机构 2022-04-15 CN disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
EP-3956346-A1 NOVEL RADIOLABELLED CXCR4-TARGETING COMPOUNDS FOR DIAGNOSIS AND THERAPY Provincial Health Services Authority (CA) 2022-02-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250242064-A1 CXCR4-TARGETING COMPOUNDS, AND METHODS OF MAKING AND USING THE SAME CXCR4, CXCL12, ACKR3 KMT2A 4385/4885MDM2 4231/4885MDM4 4337/4885
US-20220218852-A1 NOVEL RADIOLABELLED CXCR4-TARGETING COMPOUNDS FOR DIAGNOSIS AND THERAPY CXCR4, CXCR1, FPR1 KMT2A 3303/4885MDM2 3813/4885MDM4 4011/4885
US-20260124312-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 EPHA2, EPHB2, ERBB2 KMT2A 1304/4885MDM2 284/4885MDM4 4213/4885
US-20220289792-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 EPHA2, EPHB2, ERBB2 KMT2A 2073/4885MDM2 241/4885MDM4 2761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.