Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | CTSS | P25774 | 3/20 | 0.60 |
| ▸ | CTSK | P43235 | 2/20 | 0.60 |
| ▸ | CTSL | P07711 | 1/20 | 0.60 |
| ▸ | CTSB | P07858 | 1/20 | 0.60 |
| ▸ | ACE | P12821 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12203694 | 1.00 | NPC1 (0.63) | NPC1RAB9AATMCTSSCTSK | |
| SCHEMBL3676162 | 1.00 | NPC1 (0.63) | NPC1RAB9AATMCTSSCTSK | |
| SCHEMBL3676166 | 1.00 | NPC1 (0.63) | NPC1RAB9AATMCTSSCTSK | |
| Dimethylamine SCHEMBL1435916 | 0.97 | ATM (0.60) | NPC1RAB9AATMCTSSCTSK | |
| SCHEMBL18569400 | 0.94 | PPARA (0.60) | NPC1RAB9AATMCTSSCTSK | |
| SCHEMBL14884499 | 0.91 | CTSS (0.65) | NPC1RAB9AATMCTSSCTSK | |
| SCHEMBL13823611 | 0.90 | CTSS (0.57) | NPC1RAB9AATMCTSSCTSK | |
| SCHEMBL22962299 | 0.89 | CTSS (0.70) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL10135746 | 0.89 | CTSS (0.70) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL19930027 | 0.88 | BCL2 (0.59) | ATMCTSSACEPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117402085-A | Novel method for synthesizing D-N-BOC-biphenylpropylamine | 迪嘉药业集团股份有限公司 | 2024-01-16 | — | — | CN | claimed |
| CN-117402085-A | Novel method for synthesizing D-N-BOC-biphenylpropylamine | 迪嘉药业集团股份有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-114072205-A | Method of treating hypertension with TIE-2 activator | 视点制药公司 | 2022-02-18 | — | — | CN | disclosed |