Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | PRKACG | P22612 | 1/20 | 0.46 |
| ▸ | PRKACB | P22694 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25296141 | 1.00 | SRC (0.46) | SRCPRKACAPRKACGPRKACBMAPK1 | |
| SCHEMBL25300658 | 0.93 | MAPK1 (0.42) | SRCPRKACAPRKACGPRKACBMAPK1 | |
| SCHEMBL29404961 | 0.93 | MAPK1 (0.42) | SRCPRKACAPRKACGPRKACBMAPK1 | |
| SCHEMBL29404923 | 0.86 | GFER (0.38) | SRCPRKACAPRKACGPRKACBMAPK1 | |
| SCHEMBL25255812 | 0.86 | GFER (0.38) | SRCPRKACAPRKACGPRKACBMAPK1 | |
| SCHEMBL25257835 | 0.85 | L3MBTL1 (0.52) | SRCMAPK1L3MBTL1ALOX5CA12 | |
| SCHEMBL29405442 | 0.85 | L3MBTL1 (0.52) | SRCMAPK1L3MBTL1ALOX5CA12 | |
| SCHEMBL25301767 | 0.84 | KMT2A (0.41) | ALOX5GLSKMT2A | |
| SCHEMBL25255387 | 0.82 | PDE4A (0.47) | L3MBTL1HTR2CSLC6A4PDE4APDE4B | |
| SCHEMBL29404573 | 0.82 | PDE4A (0.47) | L3MBTL1HTR2CSLC6A4PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115956071-A | Imidazoquinoline or benzindazolone compounds and intermediates for their preparation | LMITO药业株式会社 | 2023-04-11 | — | — | CN | disclosed |
| WO-2022039460-A1 | IMIDAZOLQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME | 주식회사 엘마이토테라퓨틱스 | 2022-02-24 | — | — | WO | disclosed |