Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25256662 | 1.00 | KDM4E (0.42) | KDM4ELMNAHTTESR1SMN1; SMN2 | |
| SCHEMBL30253990 | 0.85 | KDM4E (0.42) | KDM4ELMNAHTTSMN1; SMN2GAA | |
| SCHEMBL31037059 | 0.81 | MPO (0.43) | KDM4ELMNAHTTESR1SMN1; SMN2 | |
| SCHEMBL25301757 | 0.79 | PDE1A (0.44) | KDM4ELMNASMN1; SMN2PDE1APDE1B | |
| SCHEMBL29402024 | 0.79 | HTT (0.43) | KDM4ELMNAHTTGAAPOLB | |
| SCHEMBL25300107 | 0.79 | HTT (0.43) | KDM4ELMNAHTTGAAPOLB | |
| SCHEMBL25256531 | 0.76 | MAPK1 (0.53) | KDM4ELMNAHTTSMN1; SMN2POLB | |
| SCHEMBL29405164 | 0.76 | MAPK1 (0.53) | KDM4ELMNAHTTSMN1; SMN2POLB | |
| SCHEMBL25300047 | 0.75 | HTT (0.40) | KDM4ELMNAHTTESR1SMN1; SMN2 | |
| SCHEMBL29402334 | 0.75 | HTT (0.40) | KDM4ELMNAHTTESR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115956071-A | Imidazoquinoline or benzindazolone compounds and intermediates for their preparation | LMITO药业株式会社 | 2023-04-11 | — | — | CN | disclosed |
| WO-2022039460-A1 | IMIDAZOLQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME | 주식회사 엘마이토테라퓨틱스 | 2022-02-24 | — | — | WO | disclosed |