SCHEMBL2940286

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2938824	0.89	MEN1 (0.42)	PDE10AMAPTKDM4EMEN1ALDH1A1
	SCHEMBL2941515	0.86	PDE10A (0.38)	PDE10AMAPTKDM4EALDH1A1HTR1A
	SCHEMBL27602880	0.84	PTPN1 (0.43)	PDE10APTPN1MEN1KMT2AHTR1A
	SCHEMBL2938247	0.83	PTPN1 (0.37)	PDE10APTPN1IRAK1IRAK4HTR2C
	SCHEMBL2940175	0.82	NOTUM (0.41)	PDE10APTPN1KDM4EIRAK1IRAK4
	SCHEMBL2938152	0.82	NOTUM (0.46)	PDE10APTPN1IRAK4ADRB1HTR2C
	SCHEMBL2939360	0.82	HTR1A (0.39)	PDE10APTPN1MAPTHTR1AHTR7
	SCHEMBL2935411	0.80	PBRM1 (0.40)	MAPTKDM4EMEN1ALDH1A1KMT2A
	SCHEMBL2939997	0.80	PTPN1 (0.37)	PDE10APTPN1IRAK1IRAK4HTR1A
	SCHEMBL2941126	0.79	NOTUM (0.39)	PDE10APTPN1ALDH1A1IRAK1IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.