Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.70 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.70 |
| ▸ | AR | P10275 | 4/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | ESR1 | P03372 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22400061 | 1.00 | PGR (0.72) | PGRCYP3A4NR3C1ARABCB11 | |
| SCHEMBL10951986 | 1.00 | PGR (0.72) | PGRCYP3A4NR3C1ARABCB11 | |
| SCHEMBL10954178 | 1.00 | PGR (0.72) | PGRCYP3A4NR3C1ARABCB11 | |
| SCHEMBL25334510 | 1.00 | PGR (0.72) | PGRCYP3A4NR3C1ARABCB11 | |
| SCHEMBL8853803 | 0.91 | PGR (0.64) | PGRCYP3A4NR3C1ARABCB11 | |
| SCHEMBL10890999 | 0.91 | PGR (0.64) | PGRCYP3A4NR3C1ARABCB11 | |
| SCHEMBL9618957 | 0.90 | PGR (0.66) | PGRCYP3A4NR3C1ARABCB11 | |
| SCHEMBL10891660 | 0.88 | PGR (0.61) | PGRCYP3A4NR3C1ARABCB11 | |
| SCHEMBL11599988 | 0.88 | PGR (0.64) | PGRCYP3A4NR3C1ARABCB11 | |
| SCHEMBL11408227 | 0.87 | PGR (0.59) | PGRCYP3A4NR3C1ARABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11274119-B2 | Industrial process for the synthesis of nomegestrol-acetate | RICHTER GEDEON NYRT. (HU) | 2022-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11274119-B2 | Industrial process for the synthesis of nomegestrol-acetate | CYP19A1, HSD17B11, CYP17A1 | PGR 29/4885CYP3A4 121/4885NR3C1 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.