SCHEMBL29403108

SCHEMBL29403108

OC(C1CO1)C(O)C(O)C(O)C(O)C1CO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250361232-A1 SUBSTITUTED ACETYLENIC PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS KINASE INHIBITORS TAKEDA PHARMACEUTICALS USA INC (US) 2025-11-27 US disclosed
CN-119735613-A Crystalline forms of 5-chloro-N4- [2- (dimethylphosphoryl) phenyl ] -N2- { 2-methoxy-4- [4- (4-methylpiperazin-1-yl) piperidin-1-yl ] phenyl } pyrimidine-2, 4-diamine 武田药品工业株式会社 2025-04-01 CN disclosed
EP-2300013-B2 PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS TAKEDA PHARMACEUTICALS CO (JP) 2024-11-13 EP disclosed
US-20240299363-A1 BENDAMUSTINE PHARMACEUTICAL COMPOSITIONS VOUDOURIS VASILIOS (US) 2024-09-12 US disclosed
US-12011432-B2 Method of modulating ribonucleotide reductase CASE WESTERN RESERVE UNIVERSITY (US) 2024-06-18 US disclosed
US-11958850-B2 Heteroaryl compounds for kinase inhibition TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-04-16 US disclosed
US-20240043457-A1 CRYSTALLINE FORMS OF 5-CHLORO-N4-[-2-(DIMETHYLPHOSPHORYL) PHENYL]-N2-{2-METHOXY-4-[4[(4-METHYLPIPERAZIN-1-YL) PIPERIDIN-1-YL] PHENYL} PYRIMIDINE-2,4-DIAMINE TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-02-08 US disclosed
US-20230321177-A1 POLYPHARMACEUTICAL DRUG COMPOSITIONS AND RELATED METHODS AVETA BIOMICS, INC. 2023-10-12 US disclosed
US-20230310381-A1 BENDAMUSTINE PHARMACEUTICAL COMPOSITIONS VOUDOURIS VASILIOS (US) 2023-10-05 US disclosed
EP-3773654-B1 POLYPHARMACEUTICAL DRUG COMPOSITIONS AND RELATED METHODS AVETA BIOMICS INC (US) 2023-09-20 EP disclosed
US-20230172911-A1 METHOD OF MODULATING RIBONUCLEOTIDE REDUCTASE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-06-08 US disclosed
US-20230102829-A1 Heteroaryl Compounds For Kinase Inhibition ARIAD PHARMACEUTICALS, INC. 2023-03-30 US disclosed
US-20230016609-A1 MESOPOROUS SILICA NANOPARTICLES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-01-19 US disclosed
US-20220380367-A1 MODIFIED CARBAZOLES AS THERAPEUTIC AGENTS THE UNIVERSITY OF MONTANA 2022-12-01 US disclosed
US-11439623-B2 Method of modulating ribonucleotide reductase CASE WESTERN RESERVE UNIVERSITY (US) 2022-09-13 US disclosed
US-11427605-B2 Crystalline forms of 5-chloro-N4-[-2-(dimethylphosphoryl) phenyl]-N2-{2-methoxy-4-[4-(4-methylpiperazin-1-yl) piperidin-1-yl] phenyl} pyrimidine-2,4-diamine TAKEDA PHARMACEUTICAL COMPANY LIMITED 2022-08-30 US disclosed
US-11420967-B2 Modified carbazoles as therapeutic agents UNIVERSITY OF WASHINGTON (US) 2022-08-23 US disclosed
US-20220079923-A1 BENDAMUSTINE PHARMACEUTICAL COMPOSITIONS VOUDOURIS VASILIOS (US) 2022-03-17 US disclosed
US-20220081440-A1 SUBSTITUTED ACETYLENIC PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS KINASE INHIBITORS TAKEDA PHARMACEUTICALS U.S.A., INC. 2022-03-17 US disclosed
US-11260127-B2 Mesoporous silica nanoparticles for diagnostic and therapeutic applications CASE WESTERN RESERVE UNIVERSITY (US) 2022-03-01 US disclosed