SCHEMBL31447843

SCHEMBL31447843

O=C1CCC(Nc2cccc(NC(=O)CN3CCC(CN4CCNCC4)CC3)c2)C(=O)N1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 11/20 0.49
▸ CRBN Q96SW2 11/20 0.49
▸ POLB P06746 1/20 0.43
▸ DRD4 P21917 4/20 0.43
▸ DRD2 P14416 2/20 0.43
▸ DRD3 P35462 2/20 0.43
▸ JAK3 P52333 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.41
▸ CYP2D6 P10635 1/20 0.41
▸ CYP2C9 P11712 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29403117 0.94 DDB1 (0.55) DDB1CRBNPOLBDRD4DRD2
SCHEMBL22118175 0.94 DDB1 (0.55) DDB1CRBNPOLBDRD4DRD2
Hydrochloric Acid SCHEMBL22117971 0.93 DDB1 (0.54) DDB1CRBNPOLBDRD4DRD2
Hydrochloric Acid SCHEMBL31174905 0.93 DDB1 (0.54) DDB1CRBNPOLBDRD4DRD2
SCHEMBL24161552 0.85 DDB1 (0.67) DDB1CRBNPOLBALDH1A1CYP2D6
SCHEMBL31447686 0.83 DDB1 (0.71) DDB1CRBN
SCHEMBL22117961 0.83 DDB1 (0.55) DDB1CRBNPOLBDRD4DRD2
SCHEMBL22128953 0.83 DDB1 (0.55) DDB1CRBNPOLBDRD4DRD2
SCHEMBL31447911 0.83 DDB1 (0.50) DDB1CRBN
SCHEMBL24290129 0.83 DDB1 (0.52) DDB1CRBNPOLBDRD4DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF UBIX THERAPEUTICS, INC. (KR) 2025-02-06 — — US claimed
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF UBIX THERAPEUTICS, INC. (KR) 2025-02-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF BTK, LYN, SYK DDB1 1245/4885CRBN 324/4885POLB 3495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback