SCHEMBL29403678

SCHEMBL29403678

C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CS)NC(=O)[C@H](CS)NC1=O

nearest known ligand 0.65

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SSTR4 P31391 14/20 0.59
▸ SSTR2 P30874 12/20 0.59
▸ SSTR5 P35346 12/20 0.59
▸ SSTR3 P32745 10/20 0.59
▸ SSTR1 P30872 4/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29356129 0.94 SSTR4 (0.65) SSTR4SSTR2SSTR5SSTR3SSTR1
SCHEMBL10827586 0.91 SSTR5 (0.68) SSTR4SSTR2SSTR5SSTR3
SCHEMBL20465923 0.87 SSTR4 (0.63) SSTR4SSTR2SSTR5SSTR3SSTR1
SCHEMBL21892057 0.86 SSTR4 (0.64) SSTR4SSTR2SSTR5SSTR3SSTR1
SCHEMBL18712834 0.86 SSTR4 (0.64) SSTR4SSTR2SSTR5SSTR3SSTR1
SCHEMBL31632617 0.86 HDAC3 (0.58) SSTR4SSTR2SSTR5SSTR3SSTR1
SCHEMBL31632622 0.86 HDAC3 (0.58) SSTR4SSTR2SSTR5SSTR3SSTR1
SCHEMBL20465752 0.86 SSTR2 (0.69) SSTR4SSTR2SSTR5SSTR3SSTR1
SCHEMBL17404638 0.85 SSTR4 (0.64) SSTR4SSTR2SSTR5SSTR3SSTR1
SCHEMBL24347633 0.84 SSTR2 (0.65) SSTR4SSTR2SSTR5SSTR3SSTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11458206-B2 Targeted conjugates and particles and formulations thereof TVA (ABC), LLC (US) 2022-10-04 — — US disclosed
US-20220251143-A1 NON-HYDROLYZABLE NON-CLEAVABLE, STABLE LINKERS FOR PRECISION THERAPEUTICS AND USES THEREOF UNIV COLUMBIA (US) 2022-08-11 — — US disclosed
US-20220096646-A1 SSTR-TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF TVA (ABC), LLC 2022-03-31 — — US disclosed
US-20220054647-A1 SSTR-TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF TVA (ABC), LLC 2022-02-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220054647-A1 SSTR-TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF SSTR1, SSTR4, SSTR3 SSTR4 2/4885SSTR2 5/4885SSTR5 4/4885
US-20220096646-A1 SSTR-TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF SSTR1, SSTR4, SSTR3 SSTR4 2/4885SSTR2 5/4885SSTR5 4/4885
US-11458206-B2 Targeted conjugates and particles and formulations thereof SSTR5, SSTR1, SSTR4 SSTR4 3/4885SSTR2 4/4885SSTR5 1/4885
US-20220251143-A1 NON-HYDROLYZABLE NON-CLEAVABLE, STABLE LINKERS FOR PRECISION THERAPEUTICS AND USES THEREOF SSTR4, SSTR1, SSTR5 SSTR4 1/4885SSTR2 5/4885SSTR5 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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