SCHEMBL29356129

SCHEMBL29356129

C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CS)NC(=O)[C@H](CS)NC1=O

nearest known ligand 0.72

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 14/20 0.65
SSTR5 P35346 13/20 0.65
SSTR2 P30874 12/20 0.65
SSTR3 P32745 7/20 0.65
SSTR1 P30872 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10827586 0.97 SSTR5 (0.68) SSTR4SSTR5SSTR2SSTR3
SCHEMBL29403678 0.94 SSTR4 (0.59) SSTR4SSTR5SSTR2SSTR3SSTR1
SCHEMBL31142116 0.87 SSTR2 (0.62) SSTR4SSTR5SSTR2SSTR3SSTR1
SCHEMBL16342328 0.86 SSTR4 (0.62) SSTR4SSTR5SSTR2SSTR3SSTR1
SCHEMBL13318791 0.86 SSTR4 (0.76) SSTR4SSTR5SSTR2SSTR3SSTR1
SCHEMBL12912365 0.86 SSTR4 (0.66) SSTR4SSTR5SSTR2SSTR3SSTR1
SCHEMBL18712557 0.85 SSTR2 (0.75) SSTR4SSTR5SSTR2SSTR3SSTR1
SCHEMBL30480651 0.85 HDAC3 (0.75) SSTR4SSTR5SSTR2SSTR3
SCHEMBL14454053 0.84 SSTR4 (0.87) SSTR4SSTR5SSTR2SSTR3SSTR1
SCHEMBL19542340 0.84 SSTR2 (0.74) SSTR4SSTR5SSTR2SSTR3SSTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250161462-A1 ENDOSOMAL CLEAVABLE HYDROPHILIC-MASKED CATIONIC CHARGE DELIVERY VEHICLES UNIV CALIFORNIA (US) 2025-05-22 US disclosed
US-20230372491-A1 ENDOSOMAL ESCAPE DOMAINS FOR DELIVERY OF MACROMOLECULES INTO CELLS UNIV CALIFORNIA (US) 2023-11-23 US disclosed
EP-4225326-A1 ENDOSOMAL ESCAPE DOMAINS FOR DELIVERY OF MACROMOLECULES INTO CELLS The Regents of the University of California (US) 2023-08-16 EP disclosed
US-11458206-B2 Targeted conjugates and particles and formulations thereof TVA (ABC), LLC (US) 2022-10-04 US disclosed
US-20220251143-A1 NON-HYDROLYZABLE NON-CLEAVABLE, STABLE LINKERS FOR PRECISION THERAPEUTICS AND USES THEREOF UNIV COLUMBIA (US) 2022-08-11 US disclosed
WO-2022081589-A1 ENDOSOMAL ESCAPE DOMAINS FOR DELIVERY OF MACROMOLECULES INTO CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-21 WO disclosed
US-20220096646-A1 SSTR-TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF TVA (ABC), LLC 2022-03-31 US disclosed
US-20220054647-A1 SSTR-TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF TVA (ABC), LLC 2022-02-24 US disclosed
EP-3941508-A1 NON-HYDROLYZABLE, NON-CLEAVABLE, STABLE LINKERS FOR PRECISION THERAPEUTICS AND USES THEREOF The Trustees of Columbia University in the City of New York (US) 2022-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220054647-A1 SSTR-TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF SSTR1, SSTR4, SSTR3 SSTR4 2/4885SSTR5 4/4885SSTR2 5/4885
US-20230372491-A1 ENDOSOMAL ESCAPE DOMAINS FOR DELIVERY OF MACROMOLECULES INTO CELLS EEA1, CLTB, TSG101 SSTR4 3591/4885SSTR5 3671/4885SSTR2 3856/4885
US-20220096646-A1 SSTR-TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF SSTR1, SSTR4, SSTR3 SSTR4 2/4885SSTR5 4/4885SSTR2 5/4885
US-11458206-B2 Targeted conjugates and particles and formulations thereof SSTR5, SSTR1, SSTR4 SSTR4 3/4885SSTR5 1/4885SSTR2 4/4885
US-20220251143-A1 NON-HYDROLYZABLE NON-CLEAVABLE, STABLE LINKERS FOR PRECISION THERAPEUTICS AND USES THEREOF SSTR4, SSTR1, SSTR5 SSTR4 1/4885SSTR5 3/4885SSTR2 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.