Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 12/20 | 0.45 |
| ▸ | JAK1 | P23458 | 11/20 | 0.44 |
| ▸ | TYK2 | P29597 | 10/20 | 0.44 |
| ▸ | JAK3 | P52333 | 8/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12471777 | 0.78 | MAP4K4 (0.62) | MAP4K4JAK2JAK1TYK2 | |
| SCHEMBL14741484 | 0.77 | PARP1 (0.45) | JAK2JAK1TYK2JAK3BCAT2 | |
| SCHEMBL28709003 | 0.77 | BCAT2 (0.41) | MAP4K4JAK2JAK3BCAT2CSNK1A1 | |
| SCHEMBL16781320 | 0.75 | CDC7 (0.53) | JAK2JAK1TYK2 | |
| SCHEMBL14758243 | 0.75 | MAP4K4 (0.42) | MAP4K4JAK2JAK1TYK2JAK3 | |
| SCHEMBL30521626 | 0.74 | IRAK4 (0.50) | MAP4K4JAK2JAK1TYK2JAK3 | |
| SCHEMBL16781321 | 0.72 | JAK2 (0.45) | MAP4K4JAK2JAK1TYK2JAK3 | |
| SCHEMBL31356910 | 0.71 | BCAT2 (0.47) | JAK2BCAT2CSNK1A1TYRO3DYRK1B | |
| SCHEMBL20567523 | 0.71 | JAK2 (0.65) | MAP4K4JAK2JAK1TYK2JAK3 | |
| SCHEMBL3458337 | 0.71 | JAK2 (0.46) | JAK2JAK1TYK2JAK3PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874491-B | N-protected pyrrolotriazine carbon glycoside compound and preparation method thereof | Shenzhen Antai weishengwu Pharmaceutical Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-116874491-A | N-protected pyrrolotriazine carbon glycoside compound and preparation method thereof | 深圳安泰维生物医药有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-114105989-A | Preparation method and application of iodo-pyrrolotriazine amine compound | 中国科学院大连化学物理研究所 | 2022-03-01 | — | — | CN | disclosed |