Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 19/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22919196 | 1.00 | ENPP2 (0.43) | ENPP2 | |
| SCHEMBL22928856 | 0.83 | HDAC1 (0.48) | ENPP2 | |
| SCHEMBL29405258 | 0.83 | ENPP2 (0.43) | ENPP2 | |
| SCHEMBL31098257 | 0.78 | ENPP2 (0.43) | ENPP2 | |
| SCHEMBL21878506 | 0.78 | ENPP2 (0.43) | ENPP2 | |
| SCHEMBL22919209 | 0.77 | ENPP2 (0.45) | ENPP2 | |
| SCHEMBL29407122 | 0.77 | ENPP2 (0.45) | ENPP2 | |
| SCHEMBL2997865 | 0.77 | APP (0.51) | — | |
| SCHEMBL21327619 | 0.77 | MRGPRX4 (0.40) | ENPP2 | |
| SCHEMBL21327422 | 0.75 | GRM5 (0.40) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118666853-A | N-methyl N- (6- (methoxy) pyridazin-3-yl) amine derivatives for the treatment of inflammatory airway diseases or fibrotic diseases | 勃林格殷格翰国际有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-114206876-B | N-methyl, N- (6- (methoxy) pyridazin-3-yl) amine derivatives as modulators of Autotaxin (ATX) for the treatment of inflammatory airway diseases or fibrotic diseases | 勃林格殷格翰国际有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-114127054-B | N-methyl, N- (6- (methoxy) pyridazin-3-yl) amine derivatives as modulators of Autotaxin (ATX) for the treatment of inflammatory airway or fibrotic diseases | 勃林格殷格翰国际有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-114206876-A | N-methyl, N- (6- (methoxy) pyridazin-3-yl) amine derivatives as Autotaxin (ATX) modulators for the treatment of inflammatory airway diseases or fibrotic diseases | 勃林格殷格翰国际有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114127054-A | N-methyl, N- (6- (methoxy) pyridazin-3-yl) amine derivatives as Autotaxin (ATX) modulators for the treatment of inflammatory airways or fibrotic diseases | 勃林格殷格翰国际有限公司 | 2022-03-01 | — | — | CN | disclosed |