Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 1.00 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 1.00 |
| ▸ | ELANE | P08246 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21055680 | 0.74 | CYP1A1 (0.58) | CYP1A1CYP1B1ELANEMEN1POLB | |
| SCHEMBL30849922 | 0.74 | CYP1A1 (0.58) | CYP1A1CYP1B1ELANEMEN1POLB | |
| SCHEMBL21055687 | 0.74 | CYP1A1 (0.58) | CYP1A1CYP1B1ELANEMEN1POLB | |
| SCHEMBL22324170 | 0.65 | HTT (0.50) | CYP1A1CYP1B1MEN1POLBKMT2A | |
| SCHEMBL29380024 | 0.65 | HTT (0.50) | CYP1A1CYP1B1MEN1POLBKMT2A | |
| SCHEMBL11469317 | 0.64 | CYP1A1 (0.46) | CYP1A1CYP1B1ELANEACHE | |
| SCHEMBL11236803 | 0.62 | ALDH1A1 (0.45) | CYP1A1CYP1B1MEN1POLBAPEX1 | |
| SCHEMBL11586407 | 0.61 | ALDH1A1 (0.43) | CYP1A1CYP1B1 | |
| SCHEMBL11586409 | 0.61 | ALDH1A1 (0.43) | CYP1A1CYP1B1 | |
| SCHEMBL28602283 | 0.60 | CHRNA7 (0.44) | CYP1A1CYP1B1MEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114155932-B | Rehabilitation physiotherapy system for preventing necrosis of limbs of scleroderma patient based on big data | 中南大学湘雅二医院 | 2022-12-27 | — | — | CN | claimed |
| CN-114155932-A | Rehabilitation physiotherapy system for preventing necrosis of limbs and limbs of scleroderma patient based on big data | 中南大学湘雅二医院 | 2022-03-08 | — | — | CN | claimed |
| CN-110382561-B | Sealing composition | 味之素株式会社 | 2023-01-31 | — | — | CN | disclosed |
| CN-114155932-B | Rehabilitation physiotherapy system for preventing necrosis of limbs of scleroderma patient based on big data | 中南大学湘雅二医院 | 2022-12-27 | — | — | CN | disclosed |
| CN-114155932-A | Rehabilitation physiotherapy system for preventing necrosis of limbs and limbs of scleroderma patient based on big data | 中南大学湘雅二医院 | 2022-03-08 | — | — | CN | disclosed |