Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 10/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 10/20 | 0.46 |
| ▸ | KCNE1 | P15382 | 7/20 | 0.46 |
| ▸ | KCNQ1 | P51787 | 7/20 | 0.46 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22659168 | 1.00 | KLKB1 (0.48) | KLKB1KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL22659359 | 0.91 | DGAT2 (0.49) | KCNQ3KCNQ2KCNE1KCNQ1DGAT2 | |
| SCHEMBL29405064 | 0.91 | DGAT2 (0.49) | KCNQ3KCNQ2KCNE1KCNQ1DGAT2 | |
| SCHEMBL22659842 | 0.90 | MCHR1 (0.51) | KCNQ3KCNQ2KCNE1KCNQ1DGAT2 | |
| SCHEMBL22659137 | 0.85 | KCNQ3 (0.47) | KCNQ3KCNQ2KCNE1KCNQ1DGAT2 | |
| SCHEMBL22659373 | 0.84 | BRAF (0.47) | DGAT2TRPV1 | |
| SCHEMBL29405925 | 0.84 | STIM1 (0.39) | KLKB1DGAT2HTR2CMCHR1 | |
| SCHEMBL22659804 | 0.84 | STIM1 (0.39) | KLKB1DGAT2HTR2CMCHR1 | |
| SCHEMBL22659311 | 0.82 | PDGFRB (0.52) | KCNQ3KCNQ2KCNE1KCNQ1DGAT2 | |
| SCHEMBL22659283 | 0.82 | TRPV1 (0.48) | KCNQ3KCNQ2KCNE1KCNQ1DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3966208-A2 | COMPOUNDS AND METHODS FOR TREATING CANCER | Antidote IP Holdings, LLC (US) | 2022-03-16 | — | — | EP | disclosed |