Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 18/20 | 0.53 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2940631 | 1.00 | IGF1R (0.53) | IGF1RTACR1HDAC6 | |
| Trifluoroacetic Acid SCHEMBL3736477 | 0.96 | IGF1R (0.49) | IGF1RTACR1HDAC6 | |
| SCHEMBL2941750 | 0.93 | IGF1R (0.50) | IGF1RHDAC6 | |
| SCHEMBL2941751 | 0.93 | IGF1R (0.50) | IGF1RHDAC6 | |
| Trifluoroacetic Acid SCHEMBL3726949 | 0.91 | IGF1R (0.47) | IGF1RHDAC6 | |
| SCHEMBL2937248 | 0.89 | IGF1R (0.51) | IGF1R | |
| SCHEMBL2937245 | 0.89 | IGF1R (0.51) | IGF1R | |
| SCHEMBL3726947 | 0.88 | IGF1R (0.46) | IGF1R | |
| Trifluoroacetic Acid SCHEMBL3727093 | 0.87 | IGF1R (0.47) | IGF1RHDAC6 | |
| SCHEMBL2941625 | 0.85 | IGF1R (0.72) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-B1 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2010-09-22 | — | — | EP | disclosed |