Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 8/20 | 0.81 |
| ▸ | KLKB1 | P03952 | 14/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29407281 | 0.92 | F11 (0.85) | F11KLKB1 | |
| SCHEMBL22981502 | 0.92 | F11 (0.85) | F11KLKB1 | |
| SCHEMBL29697514 | 0.91 | KLKB1 (0.84) | F11KLKB1 | |
| SCHEMBL29407471 | 0.89 | F11 (1.00) | F11KLKB1 | |
| SCHEMBL29388508 | 0.89 | F11 (0.81) | F11KLKB1 | |
| SCHEMBL29407457 | 0.89 | KLKB1 (0.90) | F11KLKB1 | |
| SCHEMBL29407507 | 0.88 | F11 (1.00) | F11KLKB1 | |
| SCHEMBL29405070 | 0.87 | KLKB1 (1.00) | F11KLKB1 | |
| SCHEMBL29407285 | 0.87 | F11 (0.87) | F11KLKB1 | |
| SCHEMBL22981918 | 0.87 | KLKB1 (0.81) | F11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206852-A | Plasma kallikrein inhibitors | 卡尔维斯塔制药有限公司 | 2022-03-18 | — | — | CN | disclosed |