Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.49 |
| ▸ | EGFR | P00533 | 3/20 | 0.49 |
| ▸ | ABL1 | P00519 | 2/20 | 0.48 |
| ▸ | ABL2 | P42684 | 2/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 12/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22659184 | 1.00 | SRC (0.49) | SRCEGFRABL1ABL2PIK3CD | |
| SCHEMBL29452487 | 0.81 | MAP4K4 (0.43) | SRCPIK3CDLRRK2 | |
| SCHEMBL22676912 | 0.81 | MAP4K4 (0.43) | SRCPIK3CDLRRK2 | |
| SCHEMBL22658709 | 0.80 | SRC (0.52) | SRCEGFRABL1ABL2PIK3CD | |
| SCHEMBL29407628 | 0.80 | SRC (0.52) | SRCEGFRABL1ABL2PIK3CD | |
| SCHEMBL64853 | 0.77 | RIPK1 (0.46) | SRCEGFRABL1ABL2PIK3CD | |
| SCHEMBL22132866 | 0.76 | RIPK1 (0.49) | SRCEGFRABL1ABL2PIK3CD | |
| SCHEMBL22186345 | 0.76 | RIPK1 (0.49) | SRCEGFRABL1ABL2PIK3CD | |
| SCHEMBL58551 | 0.76 | RIPK1 (0.49) | SRCEGFRABL1ABL2PIK3CD | |
| SCHEMBL31398964 | 0.75 | SRC (0.52) | SRCEGFRABL1ABL2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119874707-A | FGFR inhibitors and methods of use thereof | 传达治疗有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-114126620-B | FGFR inhibitors and methods of use thereof | 传达治疗有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-114126620-A | FGFR inhibitors and methods of use thereof | 传达治疗有限公司 | 2022-03-01 | — | — | CN | disclosed |