Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 12/20 | 0.41 |
| ▸ | JAK3 | P52333 | 11/20 | 0.41 |
| ▸ | JAK1 | P23458 | 8/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22658694 | 1.00 | LRRK2 (0.43) | LRRK2DYRK1AJAK2JAK3JAK1 | |
| SCHEMBL28685316 | 0.89 | DYRK1A (0.44) | LRRK2DYRK1AJAK2JAK3JAK1 | |
| SCHEMBL22658825 | 0.83 | SRC (0.49) | LRRK2EGFR | |
| SCHEMBL29407748 | 0.83 | SRC (0.49) | LRRK2EGFR | |
| SCHEMBL22676700 | 0.77 | DYRK1A (0.49) | LRRK2DYRK1AEGFR | |
| SCHEMBL29407719 | 0.77 | DYRK1A (0.49) | LRRK2DYRK1AEGFR | |
| SCHEMBL28700136 | 0.76 | LRRK2 (0.43) | LRRK2DYRK1AJAK2JAK3JAK1 | |
| SCHEMBL22658541 | 0.75 | FGFR1 (0.47) | LRRK2EGFR | |
| SCHEMBL26106303 | 0.74 | DYRK1A (0.51) | LRRK2DYRK1AJAK2 | |
| SCHEMBL22658709 | 0.72 | SRC (0.52) | LRRK2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119874707-A | FGFR inhibitors and methods of use thereof | 传达治疗有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-114126620-B | FGFR inhibitors and methods of use thereof | 传达治疗有限公司 | 2024-12-31 | — | — | CN | disclosed |
| EP-3968999-A1 | FGFR INHIBITORS AND METHODS OF USE THEREOF | Relay Therapeutics, Inc. (US) | 2022-03-23 | — | — | EP | disclosed |
| CN-114126620-A | FGFR inhibitors and methods of use thereof | 传达治疗有限公司 | 2022-03-01 | — | — | CN | disclosed |