Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.43 |
| ▸ | JAK2 | O60674 | 9/20 | 0.41 |
| ▸ | JAK3 | P52333 | 9/20 | 0.41 |
| ▸ | JAK1 | P23458 | 7/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22658709 | 0.86 | SRC (0.52) | LRRK2EGFRSRC | |
| SCHEMBL29407628 | 0.86 | SRC (0.52) | LRRK2EGFRSRC | |
| SCHEMBL22658959 | 0.80 | LRRK2 (0.41) | LRRK2JAK2JAK3JAK1DYRK1A | |
| SCHEMBL28685316 | 0.80 | DYRK1A (0.44) | LRRK2JAK2JAK3JAK1DYRK1A | |
| SCHEMBL28693886 | 0.76 | LCK (0.47) | EGFRBTK | |
| SCHEMBL22658694 | 0.76 | LRRK2 (0.43) | LRRK2JAK2JAK3JAK1DYRK1A | |
| SCHEMBL29407749 | 0.76 | LRRK2 (0.43) | LRRK2JAK2JAK3JAK1DYRK1A | |
| SCHEMBL22673414 | 0.73 | EGFR (0.56) | JAK2JAK3JAK1EGFRSRC | |
| SCHEMBL28690889 | 0.72 | PRMT5 (0.43) | LRRK2JAK2JAK3JAK1EGFR | |
| SCHEMBL22659128 | 0.72 | DYRK1A (0.39) | LRRK2JAK2JAK3JAK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114126620-A | FGFR inhibitors and methods of use thereof | 传达治疗有限公司 | 2022-03-01 | — | — | CN | disclosed |