Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 15/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | HCK | P08631 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | ABL2 | P42684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22676086 | 1.00 | MAP4K4 (0.39) | MAP4K4LRRK2JAK2SRCEGFR | |
| SCHEMBL29407741 | 0.89 | JAK2 (0.36) | MAP4K4JAK2PIK3CD | |
| SCHEMBL22676756 | 0.89 | JAK2 (0.36) | MAP4K4JAK2PIK3CD | |
| SCHEMBL22658544 | 0.86 | LRRK2 (0.42) | LRRK2PI4KB | |
| SCHEMBL22676912 | 0.76 | MAP4K4 (0.43) | MAP4K4LRRK2JAK2SRCPIK3CD | |
| SCHEMBL29452487 | 0.76 | MAP4K4 (0.43) | MAP4K4LRRK2JAK2SRCPIK3CD | |
| SCHEMBL22658747 | 0.74 | — | — | |
| SCHEMBL29407675 | 0.69 | POLB (0.37) | JAK2PIK3CD | |
| SCHEMBL22676898 | 0.69 | POLB (0.37) | JAK2PIK3CD | |
| SCHEMBL22659184 | 0.68 | SRC (0.49) | LRRK2SRCEGFRPIK3CDABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119874707-A | FGFR inhibitors and methods of use thereof | 传达治疗有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-114126620-B | FGFR inhibitors and methods of use thereof | 传达治疗有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-114126620-A | FGFR inhibitors and methods of use thereof | 传达治疗有限公司 | 2022-03-01 | — | — | CN | disclosed |