Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22676898 | 1.00 | POLB (0.37) | POLBCYP11B2PIK3CDSYKSCD5 | |
| SCHEMBL29452539 | 0.81 | NAMPT (0.33) | POLBCYP11B2PIK3CDSYKSCD5 | |
| SCHEMBL22676756 | 0.80 | JAK2 (0.36) | POLBPIK3CDACACBJAK2 | |
| SCHEMBL29407741 | 0.80 | JAK2 (0.36) | POLBPIK3CDACACBJAK2 | |
| SCHEMBL22658710 | 0.78 | POLB (0.36) | POLBCYP11B2PIK3CDSCD5ACACB | |
| SCHEMBL29407750 | 0.78 | POLB (0.36) | POLBCYP11B2PIK3CDSCD5ACACB | |
| SCHEMBL23326447 | 0.75 | MKNK1 (0.36) | POLBPIK3CD | |
| SCHEMBL29861463 | 0.75 | MKNK1 (0.36) | POLBPIK3CD | |
| SCHEMBL21143945 | 0.74 | CYP11B2 (0.43) | POLBCYP11B2SYKSCD5PDE4A | |
| SCHEMBL3985126 | 0.73 | POLB (0.40) | POLBNAMPTKITGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119874707-A | FGFR inhibitors and methods of use thereof | 传达治疗有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-114126620-B | FGFR inhibitors and methods of use thereof | 传达治疗有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-114126620-A | FGFR inhibitors and methods of use thereof | 传达治疗有限公司 | 2022-03-01 | — | — | CN | disclosed |