Maraciclatide

Maraciclatide

SCHEMBL29408682

CC(=NO)C(C)(C)NCCC(CCNC(=O)CCCC(=O)NCCCCC[C@@H]1NC(=O)CSC[C@H](C(=O)NCCOCCOCCOCCNC(=O)COCC(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N2)CCNC(C)(C)C(C)=NO

nearest known ligand 0.55

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ITGB3 P05106 3/20 0.55
▸ ITGAV P06756 3/20 0.55
▸ MC4R P32245 5/20 0.47
▸ MC5R P33032 5/20 0.47
▸ MC3R P41968 5/20 0.47
▸ MC1R Q01726 5/20 0.47
▸ CTSG P08311 2/20 0.46
▸ PLAU P00749 2/20 0.45
▸ ALB P02768 1/20 0.45
▸ ITGB1 P05556 1/20 0.44
▸ ITGA5 P08648 1/20 0.44
▸ TSLP Q969D9 5/20 0.44
▸ KEAP1 Q14145 1/20 0.44
▸ NFE2L2 Q16236 1/20 0.44
▸ KLKB1 P03952 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13748443 1.00 ITGB3 (0.56) ITGB3ITGAVMC4RMC5RMC3R
SCHEMBL13870381 1.00 ITGB3 (0.56) ITGB3ITGAVMC4RMC5RMC3R
SCHEMBL13748431 1.00 ITGB3 (0.56) ITGB3ITGAVMC4RMC5RMC3R
SCHEMBL14324942 0.97 ITGB3 (0.53) ITGB3ITGAVMC4RMC5RMC3R
SCHEMBL12353644 0.96 ITGB3 (0.51) ITGB3ITGAVMC4RMC5RMC3R
SCHEMBL12353684 0.95 ITGB3 (0.50) ITGB3ITGAVMC4RMC5RMC3R
SCHEMBL12462751 0.95 ITGB3 (0.49) ITGB3ITGAVMC4RMC5RMC3R
SCHEMBL13061299 0.95 ITGB3 (0.49) ITGB3ITGAVMC4RMC5RMC3R
SCHEMBL20809940 0.95 ITGB3 (0.49) ITGB3ITGAVMC4RMC5RMC3R
SCHEMBL13887996 0.95 ITGB3 (0.49) ITGB3ITGAVMC4RMC5RMC3R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025233638-A1 RADIOPHARMACEUTICAL IMAGING METHOD OF ADENOMYOSIS SERAC HEALTHCARE LTD (GB) 2025-11-13 — — WO claimed
US-20250186633-A1 METHODS FOR IMAGING INTEGRIN EXPRESSION AND FOR IMAGING SITES OF ENDOMETRIOSIS SERAC HEALTHCARE LTD (GB) 2025-06-12 — — US claimed
EP-4486396-A1 METHODS FOR IMAGING INTEGRIN EXPRESSION AND FOR IMAGING SITES OF ENDOMETRIOSIS Serac Healthcare Ltd (GB) 2025-01-08 — — EP claimed
CN-118785926-A Imaging integrin expression and intrauterine method for imaging a site of endometriosis 赛瑞科医疗有限公司 2024-10-15 — — CN claimed
WO-2023239953-A2 IMAGING OF MATRIX METALLOPROTEINASE INHIBITORS MICROVIDE, LLC (US) 2023-12-14 — — WO claimed
WO-2023166305-A1 METHODS FOR IMAGING INTEGRIN EXPRESSION AND FOR IMAGING SITES OF ENDOMETRIOSIS SERAC HEALTHCARE LTD (GB) 2023-09-07 — — WO claimed
US-11723991-B2 Radiopharmaceutical compositions SERAC HEALTHCARE LIMITED (GB) 2023-08-15 — — US claimed
EP-3129065-B1 TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS AKAMARA THERAPEUTICS INC (US) 2026-05-13 — — EP disclosed
US-12605447-B2 Stable formulations for radionuclide complexes ITM SOLUCIN GMBH (DE) 2026-04-21 — — US disclosed
EP-4168492-B1 NEAR-INFRARED CYANINE DYES AND CONJUGATES THEREOF BRACCO IMAGING SPA (IT) 2025-12-24 — — EP disclosed
WO-2025233638-A1 RADIOPHARMACEUTICAL IMAGING METHOD OF ADENOMYOSIS SERAC HEALTHCARE LTD (GB) 2025-11-13 — — WO disclosed
WO-2025233638-A1 RADIOPHARMACEUTICAL IMAGING METHOD OF ADENOMYOSIS SERAC HEALTHCARE LTD (GB) 2025-11-13 — — WO disclosed
US-20250186633-A1 METHODS FOR IMAGING INTEGRIN EXPRESSION AND FOR IMAGING SITES OF ENDOMETRIOSIS SERAC HEALTHCARE LTD (GB) 2025-06-12 — — US disclosed
WO-2022129336-A1 PH RESPONSIVE CYANINE DYES AND CONJUGATES THEREOF BRACCO IMAGING SPA (IT) 2022-06-23 — — WO disclosed
WO-2022112323-A1 STABLE FORMULATIONS FOR RADIONUCLIDE COMPLEXES ITM SOLUCIN GMBH (DE) 2022-06-02 — — WO disclosed
WO-2022111800-A1 STABLE FORMULATIONS FOR RADIONUCLIDE COMPLEXES ITM SOLUCIN GMBH (DE) 2022-06-02 — — WO disclosed
WO-2022096673-A1 COMBINATION OF PARA-AMINOHIPPURIC ACID (PAH) AND RADIOLABELED COMPLEXES FOR TREATING CANCER ITM Isotopen Technologien München AG (DE) 2022-05-12 — — WO disclosed
WO-2022096103-A1 COMBINATION OF PARA-AMINOHIPPURIC ACID (PAH) AND RADIOLABELED COMPLEXES FOR TREATING CANCER ITM Isotopen Technologien München AG (DE) 2022-05-12 — — WO disclosed
EP-3965751-A1 PARA-AMINOHIPPURIC ACID (PAH) AS A RENAL PROTECTIVE SUBSTANCE ITM Isotope Technologies Munich SE (DE) 2022-03-16 — — EP disclosed
CN-114126654-A Para-aminohippuric acid (PAH) as a kidney protective substance 同位素技术慕尼黑有限公司 2022-03-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605447-B2 Stable formulations for radionuclide complexes EPOR, CD47, PRCP ITGB3 1415/4885ITGAV 861/4885MC4R 156/4885
US-11723991-B2 Radiopharmaceutical compositions TYMP, KIT, CHEK1 ITGB3 2816/4885ITGAV 3650/4885MC4R 576/4885
US-20250186633-A1 METHODS FOR IMAGING INTEGRIN EXPRESSION AND FOR IMAGING SITES OF ENDOMETRIOSIS ITGB3, ITGB5, ITGAV ITGB3 1/4885ITGAV 3/4885MC4R 1473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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