Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 14/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.60 |
| ▸ | KDM6A | O15550 | 5/20 | 0.55 |
| ▸ | KDM5A | P29375 | 3/20 | 0.55 |
| ▸ | KDM5C | P41229 | 3/20 | 0.55 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.55 |
| ▸ | KDM6B | O15054 | 2/20 | 0.55 |
| ▸ | KDM4A | O75164 | 2/20 | 0.55 |
| ▸ | KDM4B | O94953 | 2/20 | 0.55 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.55 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.55 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18492973 | 1.00 | HDAC1 (0.66) | HDAC1HDAC6KDM6AKDM5AKDM5C | |
| SCHEMBL18492980 | 0.88 | HDAC1 (0.66) | HDAC1HDAC6KDM6AKDM5AKDM5C | |
| SCHEMBL2722008 | 0.85 | HDAC1 (0.61) | HDAC1HDAC6KDM6AKDM5AKDM5C | |
| SCHEMBL18492972 | 0.84 | KDM6A (0.64) | HDAC1HDAC6KDM6AKDM5AKDM5C | |
| SCHEMBL29409212 | 0.84 | KDM6A (0.64) | HDAC1HDAC6KDM6AKDM5AKDM5C | |
| SCHEMBL18492977 | 0.80 | KDM6A (0.62) | HDAC1HDAC6KDM6AKDM5AKDM5C | |
| SCHEMBL10158456 | 0.78 | KDM6A (0.60) | HDAC1HDAC6KDM6AKDM5AKDM5C | |
| SCHEMBL25189604 | 0.78 | KDM6A (0.62) | HDAC1HDAC6KDM6AKDM5AKDM5C | |
| SCHEMBL10157012 | 0.78 | HDAC1 (0.58) | HDAC1HDAC6KDM6AKDM5AKDM5C | |
| SCHEMBL10157756 | 0.78 | KDM6A (0.59) | HDAC1HDAC6KDM6AKDM5AKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3962559-A1 | METHODS AND COMPOSITIONS FOR TREATING CHRONIC INFLAMMATORY INJURY, METAPLASIA, DYSPLASIA AND CANCERS OF EPITHELIAL TISSUES | University of Houston System (US) | 2022-03-09 | — | — | EP | disclosed |