Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 11/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37599856 | 1.00 | CFTR (0.59) | CFTRLMNAPKMMEN1MAPT | |
| SCHEMBL28566774 | 1.00 | CFTR (0.59) | CFTRLMNAPKMMEN1MAPT | |
| SCHEMBL29409308 | 0.88 | NR1D1 (0.61) | CFTRLMNAPKMNR1D1HTR1A | |
| SCHEMBL28912058 | 0.88 | NR1D1 (0.61) | CFTRLMNAPKMNR1D1HTR1A | |
| SCHEMBL29409296 | 0.85 | CFTR (0.57) | CFTRLMNAPKMHTR1AHTR7 | |
| SCHEMBL28560316 | 0.85 | CFTR (0.57) | CFTRLMNAPKMHTR1AHTR7 | |
| SCHEMBL28560542 | 0.83 | CFTR (0.66) | CFTRLMNAPKMHTR1AHTR7 | |
| SCHEMBL29409299 | 0.83 | CFTR (0.66) | CFTRLMNAPKMHTR1AHTR7 | |
| SCHEMBL14059108 | 0.82 | SLC22A12 (0.54) | CFTRLMNAPKMGAA | |
| SCHEMBL8721845 | 0.82 | NR1D1 (0.53) | CFTRLMNAPKMMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12377119-B2 | Natural killer cells | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2025-08-05 | — | — | US | disclosed |
| US-20220073880-A1 | NATURAL KILLER CELLS | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2022-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220073880-A1 | NATURAL KILLER CELLS | PBK, IKZF3, IKZF1 | CFTR 1048/4885LMNA 2561/4885PKM 1560/4885 |
| US-12377119-B2 | Natural killer cells | PBK, IKZF3, IKZF1 | CFTR 1048/4885LMNA 2561/4885PKM 1560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.