Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.60 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.35 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL137377 | 1.00 | EGFR (0.60) | EGFRPIK3CDPIK3CAMKNK2KDM4E | |
| Hydrochloric Acid SCHEMBL31066682 | 0.98 | EGFR (0.58) | EGFRPIK3CDPIK3CAMKNK2KDM4E | |
| Hydrochloric Acid SCHEMBL322987 | 0.98 | EGFR (0.58) | EGFRPIK3CDPIK3CAMKNK2KDM4E | |
| SCHEMBL29409356 | 0.83 | EGFR (0.58) | EGFRPIK3CDPIK3CAMKNK2KDM4E | |
| SCHEMBL88606 | 0.83 | EGFR (0.58) | EGFRPIK3CDPIK3CAMKNK2KDM4E | |
| SCHEMBL29976830 | 0.82 | EGFR (0.47) | EGFRPIK3CDPIK3CAMKNK2KDM4E | |
| Trifluoroacetic Acid SCHEMBL30391689 | 0.82 | EGFR (0.43) | EGFR | |
| Trifluoroacetic Acid SCHEMBL29977443 | 0.82 | EGFR (0.43) | EGFR | |
| Hydrochloric Acid SCHEMBL30749407 | 0.81 | EGFR (0.56) | EGFRPIK3CDPIK3CAMKNK2KDM4E | |
| Hydrochloric Acid SCHEMBL30749417 | 0.81 | EGFR (0.56) | EGFRPIK3CDPIK3CAMKNK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307534-A | LTA4H inhibitors and uses thereof | 上海海雁医药科技有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-117980310-A | Alkylene derivatives as KRAS inhibitors | 尼坎治疗公司 | 2024-05-03 | — | — | CN | claimed |
| WO-2023284730-A1 | ALKYLIDENE DERIVATIVES AS KRAS INHIBITORS | NIKANG THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | WO | claimed |
| CN-114085220-A | Substituted morpholine-4-carboxylic ester derivatives, their compositions and their medical use | 上海海雁医药科技有限公司 | 2022-02-25 | — | — | CN | claimed |
| CN-122094949-A | Compound for organic electronic element, organic electronic element using the same, and electronic device using the same | — | 2026-05-26 | — | — | CN | disclosed |
| CN-122069897-A | Organic light emitting display and electronic device thereof | 德山新勒克斯有限公司 | 2026-05-19 | — | — | CN | disclosed |
| WO-2026078529-A1 | SOLID AND DEUTERATED FORMS OF PYRIDO[4,3-D]PYRIMIDINE COMPOUNDS | PFIZER INC. (US) | 2026-04-16 | — | — | WO | disclosed |
| WO-2026078529-A1 | SOLID AND DEUTERATED FORMS OF PYRIDO[4,3-D]PYRIMIDINE COMPOUNDS | PFIZER INC. (US) | 2026-04-16 | — | — | WO | disclosed |
| EP-4705301-A2 | PYRIDO[4,3-D]PYRIMIDINE DERIVATIVES AS MUTANT KRAS G12C INHIBITORS FOR THE TREATMENT OF CANCER | Frontier Medicines Corporation (US) | 2026-03-11 | — | — | EP | disclosed |
| EP-4705300-A1 | PYRIDO[4,3-D]PYRIMIDINE DERIVATIVES AS MUTANT KRAS G12C INHIBITORS FOR THE TREATMENT OF CANCER | Frontier Medicines Corporation (US) | 2026-03-11 | — | — | EP | disclosed |
| EP-4705302-A1 | PYRIDO[4,3-D]PYRIMIDINE DERIVATIVES AS MUTANT KRAS G12C INHIBITORS FOR THE TREATMENT OF CANCER | Frontier Medicines Corporation (US) | 2026-03-11 | — | — | EP | disclosed |
| EP-4705302-A1 | PYRIDO[4,3-D]PYRIMIDINE DERIVATIVES AS MUTANT KRAS G12C INHIBITORS FOR THE TREATMENT OF CANCER | Frontier Medicines Corporation (US) | 2026-03-11 | — | — | EP | disclosed |
| CN-114616265-A | Production of lignin fragments with functional groups | 洛桑联邦理工学院 | 2022-06-10 | — | — | CN | disclosed |
| CN-114478528-A | Aroyl-substituted tricyclic compound, preparation method and application thereof | 劲方医药科技(上海)有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114380945-A | Resin, resin composition and display device using the same | 德山新勒克斯有限公司 | 2022-04-22 | — | — | CN | disclosed |
| WO-2022075486-A1 | NOVEL BICYCLIC COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2022-04-14 | — | — | WO | disclosed |
| CN-114269751-A | Optically pure oxaspiro-substituted pyrrolopyrazole derivatives, preparation method and medical application thereof | 上海海雁医药科技有限公司 | 2022-04-01 | — | — | CN | disclosed |
| WO-2022063101-A1 | AROYL SUBSTITUTED TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2022-03-31 | — | — | WO | disclosed |
| CN-114222743-A | Oxoaxamembered ring pyrimidine compounds, preparation method and medical application thereof | 劲方医药科技(上海)有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-114085220-A | Substituted morpholine-4-carboxylic ester derivatives, their compositions and their medical use | 上海海雁医药科技有限公司 | 2022-02-25 | — | — | CN | disclosed |