SCHEMBL29409598

CC[C@H](C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	TFPI	P10646	1/20	0.61

▸	VIPR1	P32241	3/20	0.59

▸	EP300	Q09472	1/20	0.59

▸	HIF1A	Q16665	1/20	0.59

▸	KISS1R	Q969F8	2/20	0.59

▸	VIPR2	P41587	5/20	0.58

▸	ECE1	P42892	1/20	0.57

▸	GLP1R	P43220	1/20	0.57

▸	MUS81	Q96NY9	1/20	0.57

▸	NPY1R	P25929	2/20	0.56

▸	NPY2R	P49146	2/20	0.56

▸	NPY4R	P50391	2/20	0.56

▸	NPY5R	Q15761	2/20	0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31000926	0.92	GLP1R (0.65)	TFPIVIPR1EP300HIF1AVIPR2
SCHEMBL29580062	0.91	VIPR1 (0.63)	VIPR1KISS1RVIPR2NPY1RNPY2R
SCHEMBL30432941	0.91	VIPR1 (0.63)	TFPIVIPR1KISS1RVIPR2ECE1
SCHEMBL29557832	0.90	KISS1R (0.61)	TFPIVIPR1KISS1RVIPR2NPY1R
SCHEMBL30512795	0.90	KISS1R (0.62)	TFPIVIPR1KISS1RVIPR2ECE1
SCHEMBL31683281	0.90	VIPR1 (0.72)	TFPIVIPR1VIPR2ECE1GLP1R
SCHEMBL30648475	0.90	GLP1R (0.61)	TFPIVIPR1KISS1RVIPR2ECE1
SCHEMBL29678375	0.89	KISS1R (0.60)	TFPIVIPR1EP300HIF1AKISS1R
SCHEMBL29746772	0.88	KISS1R (0.60)	TFPIVIPR1KISS1RVIPR2NPY1R
SCHEMBL31563800	0.88	VIPR1 (0.73)	TFPIVIPR1VIPR2ECE1GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20250263480-A1	Clazakizumab in the Treatment of Chronic Antibody-Mediated Rejection of Organ Transplant	CEDARS-SINAI MEDICAL CENTER (US)	2025-08-21	—	—	US	disclosed
CN-112969711-B	Desensitization and improvement of kidney transplantation in HLA sensitized patients using cladagumab	西达赛奈医疗中心	2024-12-17	—	—	CN	disclosed
CN-113194996-B	Clazazumab for the treatment of chronic antibody-mediated organ transplant rejection	西达赛奈医疗中心	2024-06-28	—	—	CN	disclosed
US-20220073605-A1	CLAZAKIZUMAB IN THE TREATMENT OF CHRONIC ANTIBODY-MEDIATED REJECTION OF ORGAN TRANSPLANT	CEDARS-SINAI MEDICAL CENTER (US)	2022-03-10	—	—	US	disclosed