Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.76 |
| ▸ | MAPT | P10636 | 12/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22589451 | 1.00 | TP53 (0.76) | TP53MAPTALDH1A1LMNAHPGD | |
| SCHEMBL28708741 | 0.95 | TP53 (0.70) | TP53MAPTALDH1A1LMNAHPGD | |
| SCHEMBL8885467 | 0.89 | TP53 (0.59) | TP53MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22366554 | 0.86 | TP53 (1.00) | TP53MAPTALDH1A1LMNAHPGD | |
| SCHEMBL30923536 | 0.86 | TP53 (1.00) | TP53MAPTALDH1A1LMNAHPGD | |
| SCHEMBL29409639 | 0.86 | TP53 (1.00) | TP53MAPTALDH1A1LMNAHPGD | |
| SCHEMBL22602141 | 0.83 | TP53 (0.79) | TP53MAPTALDH1A1LMNAHPGD | |
| SCHEMBL22601878 | 0.82 | TP53 (0.73) | TP53MAPTALDH1A1LMNAHPGD | |
| SCHEMBL22601936 | 0.81 | TP53 (0.72) | TP53MAPTALDH1A1LMNAHPGD | |
| SCHEMBL22589520 | 0.81 | TP53 (0.71) | TP53MAPTALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3959197-A1 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2022-03-02 | — | — | EP | disclosed |