Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 10/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29409639 | 1.00 | TP53 (1.00) | TP53MAPTALDH1A1LMNAHPGD | |
| SCHEMBL22366554 | 1.00 | TP53 (1.00) | TP53MAPTALDH1A1LMNAHPGD | |
| SCHEMBL22602141 | 0.89 | TP53 (0.79) | TP53MAPTALDH1A1LMNAHPGD | |
| SCHEMBL22601925 | 0.88 | TP53 (0.78) | TP53MAPTALDH1A1LMNAHPGD | |
| SCHEMBL22589512 | 0.87 | TP53 (0.77) | TP53MAPTALDH1A1LMNAHPGD | |
| SCHEMBL29409632 | 0.87 | TP53 (0.77) | TP53MAPTALDH1A1LMNAHPGD | |
| SCHEMBL29409648 | 0.86 | TP53 (0.76) | TP53MAPTALDH1A1LMNAHPGD | |
| SCHEMBL22589451 | 0.86 | TP53 (0.76) | TP53MAPTALDH1A1LMNAHPGD | |
| SCHEMBL22589617 | 0.86 | TP53 (0.75) | TP53MAPTALDH1A1LMNAHPGD | |
| SCHEMBL22589555 | 0.85 | TP53 (0.73) | TP53MAPTALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105450-A2 | MIRNA DYSREGULATION CORRECTION AS A STRATEGY TO TREAT HUNTINGTON'S DISEASE | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2024-05-23 | — | — | WO | claimed |
| WO-2024105450-A3 | MIRNA DYSREGULATION CORRECTION AS A STRATEGY TO TREAT HUNTINGTON'S DISEASE | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2024-10-31 | — | — | WO | disclosed |
| WO-2024105450-A8 | MIRNA DYSREGULATION CORRECTION AS A STRATEGY TO TREAT HUNTINGTON'S DISEASE | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2024-07-25 | — | — | WO | disclosed |
| WO-2024105450-A2 | MIRNA DYSREGULATION CORRECTION AS A STRATEGY TO TREAT HUNTINGTON'S DISEASE | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024105450-A2 | MIRNA DYSREGULATION CORRECTION AS A STRATEGY TO TREAT HUNTINGTON'S DISEASE | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2024-05-23 | — | — | WO | disclosed |