Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 13/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 13/20 | 0.41 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2011756 | 1.00 | LPL (0.41) | LPLLIPGBACE1ROCK1CA1 | |
| SCHEMBL29409998 | 1.00 | LPL (0.41) | LPLLIPGBACE1ROCK1CA1 | |
| SCHEMBL2010946 | 0.91 | LPL (0.39) | LPLLIPGBACE1ROCK1CA1 | |
| SCHEMBL2225037 | 0.89 | BACE1 (0.43) | LPLLIPGBACE1ROCK1CA1 | |
| SCHEMBL31394725 | 0.84 | LPL (0.41) | LPLLIPGBACE1ROCK1CA1 | |
| SCHEMBL2012175 | 0.81 | LPL (0.44) | LPLLIPGBACE1CA1CA2 | |
| SCHEMBL29502333 | 0.81 | LPL (0.47) | LPLLIPGBACE1ROCK1CA1 | |
| SCHEMBL16639375 | 0.81 | LPL (0.47) | LPLLIPGBACE1ROCK1CA1 | |
| SCHEMBL24335646 | 0.79 | BACE1 (0.44) | LPLLIPGBACE1ROCK1CA1 | |
| SCHEMBL2016481 | 0.79 | LPL (0.40) | LPLLIPGBACE1ROCK1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3968983-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | F. Hoffmann-La Roche AG (CH) | 2022-03-23 | — | — | EP | disclosed |