Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30989135 | 1.00 | ALOX15 (0.45) | ALOX15ALOX12BACE1POLBRECQL | |
| SCHEMBL10418587 | 0.87 | BACE1 (0.43) | ALOX15ALOX12BACE1POLBRECQL | |
| SCHEMBL1179824 | 0.85 | ALOX15 (0.45) | ALOX15ALOX12BACE1POLBRECQL | |
| SCHEMBL5586815 | 0.83 | ALOX15 (0.43) | ALOX15ALOX12BACE1POLBRECQL | |
| SCHEMBL11528069 | 0.83 | ALOX15 (0.43) | ALOX15ALOX12BACE1POLBRECQL | |
| SCHEMBL29668358 | 0.83 | ALOX15 (0.43) | ALOX15ALOX12BACE1POLBRECQL | |
| SCHEMBL1760472 | 0.83 | ALOX15 (0.43) | ALOX15ALOX12BACE1POLBRECQL | |
| SCHEMBL8754778 | 0.81 | ALOX15 (0.42) | ALOX15ALOX12BACE1POLBRECQL | |
| SCHEMBL30523811 | 0.81 | ALOX15 (0.42) | ALOX15ALOX12BACE1POLBRECQL | |
| SCHEMBL168554 | 0.81 | GRIN2D (0.36) | ALOX15ALOX12POLBHTTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118355911-A | Agricultural composition for preventing and treating tobacco black shank and application thereof | 贵州省烟草科学研究院 | 2024-07-19 | — | — | CN | claimed |
| CN-111900252-A | Flexible TFT device and preparation method thereof | 广东省半导体产业技术研究院 | 2020-11-06 | — | — | CN | claimed |
| CN-116171988-B | Application of 4-propylphenol in soil-borne disease control | 山东农业大学 | 2025-06-24 | — | — | CN | disclosed |
| CN-119798046-A | Method for recovering phenol from waste polycarbonate plastic | 东南大学 | 2025-04-11 | — | — | CN | disclosed |
| CN-118459321-A | Method for obtaining C6 monophenol by selectively hydrogenolyzing lignin | 东南大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-118355911-A | Agricultural composition for preventing and treating tobacco black shank and application thereof | 贵州省烟草科学研究院 | 2024-07-19 | — | — | CN | disclosed |
| CN-118355911-A | Agricultural composition for preventing and treating tobacco black shank and application thereof | 贵州省烟草科学研究院 | 2024-07-19 | — | — | CN | disclosed |
| CN-118122361-A | Method for preparing C2-phenol monomer by hydrogenolysis of lignin by using nickel-based alkaline carrier catalyst | 东南大学 | 2024-06-04 | — | — | CN | disclosed |
| CN-118122361-A | Method for preparing C2-phenol monomer by hydrogenolysis of lignin by using nickel-based alkaline carrier catalyst | 东南大学 | 2024-06-04 | — | — | CN | disclosed |
| CN-116171988-A | Application of 4-propylphenol in soil-borne disease control | 山东农业大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-113057162-B | Application of 4-ethylphenol in prevention and treatment of tobacco black shank | 山东农业大学 | 2022-02-08 | — | — | CN | disclosed |
| EP-2287162-A1 | Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of cns disorders | Otsuka Pharmaceutical Co., Ltd. (JP) | 2011-02-23 | — | — | EP | disclosed |
| EP-2287161-A1 | Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of cns disorders | Otsuka Pharmaceutical Co., Limited (JP) | 2011-02-23 | — | — | EP | disclosed |
| EP-1919907-B1 | HETEROCYCLIC COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2011-02-23 | — | — | EP | disclosed |
| EP-2284169-A1 | Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of CNS disorders | Otsuka Pharmaceutical Co., Limited (JP) | 2011-02-16 | — | — | EP | disclosed |
| US-20090264404-A1 | Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of cns disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-10-22 | — | — | US | disclosed |
| CN-101258147-A | 4-piperazin-1-yl-4-benzo [ B ] thiophene derivatives for the treatment of CNS disorders | OTSUKA PHARMA CO LTD (JP) | 2008-09-03 | — | — | CN | disclosed |
| EP-1919907-A2 | HETEROCYCLIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |
| US-3945891-A | Distillation process for purification of triaryl phosphate esters | FMC CORPORATION (US) | 1976-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264404-A1 | Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of cns disorders | GRIN2C, GRIN2B, PMP22 | ALOX15 3509/4885ALOX12 3330/4885BACE1 1859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.